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Drug-Target Interaction

Drug

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PubChem ID:231224
Structure:
Synonyms:
50-07-7
7-Amino-9.alpha.-methoxymitosane
Ametycin
Ametycine
Azirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione, 6-amino-1,1a,2,8,8a,8b-hexahydro-8-(hydroxymethyl)-8a- methoxy-5-methyl-, carbamate (ester)
Azirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione, 6-amino-8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b- hexahydro-8a-methoxy-5-methyl-, [1aR-(1a.alpha.,8.beta.,8a.alpha.,8b.alpha.)]-
Mit-C
Mito-C
Mitocin-C
MITOMYCIN
Mitomycin C
Mitomycine
Mitomycinum
MMC
Mutamycin
Mytomycin
NCI-C04706
NCI60_002199
NSC26980
WLN: T D3 B556 BN EM JV MVTTT&J GO1 H1OVZ KZ L1
[(1ar,8r,8as,8br)-6-amino-8a-methoxy-5-methyl-4,7-dioxo-1,1a,2,4,7,8,8a,8b
ATC-Codes:
Side-Effects:
Side-EffectFrequency
fibrosis0.0010
diarrhea0
burning sensation0
vomiting0
pulmonary edema0
pain0
hematemesis0
hypertension0
nausea0
thrombophlebitis0
anorexia0
alopecia0
dermatological problem0
syncope0
malaise0
somnolence0
leukopenia0
cancer0
asthenia0
ards0
erythema0
cellulitis0
fever0
blurred vision0
congestive heart failure0
cough0
thrombocytopenia0
confusion0
ulcer0
edema0
stomatitis0
hemolytic anemia0
renal failure0
dyspnea0
anemia0
fatigue0
headache0

Target

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Uniprot ID:CP1A2_HUMAN
Synonyms:
CYPIA2
Cytochrome P450 1A2
P(3)450
P450 4
P450-P3
EC-Numbers:1.14.14.1
Organism:Homo sapiens
Human
PDB IDs:2HI4
Structure:
2HI4

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
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References: