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Drug-Target Interaction

Drug

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PubChem ID:2244
Structure:
Synonyms:
11126-35-5
11126-37-7
1oxr
2-(AcetYl-Oxy)Benzoic Acid
2-(Acetyloxy)benzoic acid
2-Acetoxybenzenecarboxylic acid
2-Acetoxybenzoic acid
2-acetyloxybenzoic acid
2-Carboxyphenyl acetate
2349-94-2
26914-13-6
4-10-00-00138 (Beilstein Handbook Reference)
50-78-2
8-HOUR BAYER
98201-60-6
A 5376
A.S.A
A.S.A.
A.S.A. and Codeine Compound
A.S.A. Empirin
A2093_SIGMA
A3160_SIGMA
A5376_SIGMA
A6810_SIGMA
AB1003266
AC 5230
AC1L1D8U
AC1Q1LA0
Acenterine
Acesal
Acetal
ACETAMINOPHEN, ASPIRIN AND CAFFEINE
ACETAMINOPHEN, ASPIRIN, AND CODEINE PHOSPHATE
Aceticyl
Acetilsalicilico
Acetilum acidulatum
Acetisal
Acetol
Acetol (VAN)
Acetonyl
Acetophen
Acetosal
Acetosalic acid
Acetosalin
Acetoxybenzoic acid
Acetylin
Acetylsal
Acetylsalicylate
Acetylsalicylic acid
ACETYLSALICYLIC ACID, ASPIRIN
Acetylsalicylsaeure
Acetylsalicylsaure
Acetylsalicylsaure (GERMAN)
Acetylsalicylsaure [German]
Acetylsalycilic acid
Acetysal
Acetysalicylic acid
Acid, Acetylsalicylic
acide 2-(acetyloxy)benzoique
Acide acetylsalicylique
Acide acetylsalicylique (FRENCH)
Acide acetylsalicylique [French]
Acido acetilsalicilico
Acido acetilsalicilico [Italian]
Acido O-acetil-benzoico
Acido O-acetil-benzoico [Italian]
Acidum acetylsalicylicum
Acimetten
Acisal
Acylpyrin
Adiro
AGGRENOX
AI3-02956
AIDS-006788
AIDS006788
AIN
AKOS000118884
Aloxiprimum
Anacin
Anacin Maximum Strength
Arthritis Pain Formula Maximum Strength
ASA
Asacard
Asagran
Asatard
Ascoden-30
Ascriptin
Aspalon
Aspalon (JAN)
Aspec
Aspergum
Aspir-Mox
Aspirdrops
Aspirin
Aspirin (JP15/USP)
Aspirin (JP16/USP)
ASPIRIN AND CAFFEINE W/ BUTALBITAL
Aspirin [BAN:JAN]
Aspirina 03
Aspirine
Asprin
Aspro
Aspro Clear
Asteric
Axotal
AZDONE
Azetylsalizylsaeure
BAY-1019036
Bay-e-4465
Bayer
Bayer Aspirin 8 Hour
Bayer Buffered
Bayer Children's Aspirin
Bayer Enteric 325 mg Regular Strength
Bayer Enteric 500 mg Arthritis Strength
Bayer Enteric 81 mg Adult Low Strength
Bayer Extra Strength Aspirin for Migraine Pain
Bayer Plus
Benaspir
Benzoic acid, 2-(acetyloxy)-
Bi-prin
Bialpirina
Bialpirinia
BIDD:GT0118
BRN 0779271
Bufferin
BUTAL COMPOUND
BUTALBITAL ASPIRIN AND CAFFEINE
BUTALBITAL COMPOUND
BUTALBITAL W/ ASPIRIN & CAFFEINE
BUTALBITAL, ASPIRIN & CAFFEINE
BUTALBITAL, ASPIRIN AND CAFFEINE
BUTALBITAL, ASPIRIN, CAFFEINE, AND CODEINE PHOSPHATE
C01405
C9H8O4
Caprin
Cardioaspirin
CARISOPRODOL AND ASPIRIN
CARISOPRODOL COMPOUND
CARISOPRODOL, ASPIRIN AND CODEINE PHOSPHATE
CCG-39490
CCRIS 3243
Cemirit
CHEBI:15365
CHEMBL25
Claradin
Clariprin
cMAP_000006
CODEINE, ASPIRIN, APAP FORMULA NO. 2
CODEINE, ASPIRIN, APAP FORMULA NO. 3
CODEINE, ASPIRIN, APAP FORMULA NO. 4
CODOXY
Colfarit
component of A.S.A. and Codeine Compound
component of A.S.A. Compound
component of Ansemco 2
component of Ascodeen-30
component of Coricidin
component of Darvon with A.S.A
component of Midol
component of Percobarb
component of Percodan
component of Persistin
component of Phensal
component of Robaxisal
component of St. Joseph Cold Tablets
component of Synirin
component of Zactirin
COMPOUND 65
Contrheuma retard
Crystar
D00109
D001241
D41527A7-A9EB-472D-A7FC-312821130549
DARVON COMPOUND
DARVON COMPOUND-65
DARVON W/ ASA
DARVON-N W/ ASA
Dasin
DB00945
DEA No. 9804
Decaten
Delgesic
Dispril
DivK1c_000555
Dolean pH 8
Duramax
Easprin
Easprin (TN)
ECM
Ecolen
Ecotrin
EINECS 200-064-1
Empirin
Empirin with Codeine
Endosprin
Endydol
Entericin
Enterophen
Enterosarein
Enterosarine
Entrophen
Equagesic
EU-0100038
EXCEDRIN (MIGRAINE)
Extren
FIORINAL
FIORINAL W/CODEINE NO 3
Globentyl
Globoid
Helicon
HMS1920E13
HMS2090G03
HMS2091K13
HMS2233L18
HMS3260G17
HMS501L17
HSDB 652
I14-7505
IDI1_000555
Idragin
INVAGESIC
INVAGESIC FORTE
Istopirin
Kapsazal
KBio1_000555
KBio2_001725
KBio2_002271
KBio2_004293
KBio2_004839
KBio2_006861
KBio2_007407
KBio3_002149
KBio3_002751
KBioGR_000398
KBioGR_002271
KBioSS_001725
KBioSS_002272
Kyselina 2-acetoxybenzoova
Kyselina 2-acetoxybenzoova [Czech]
Kyselina acetylsalicylova
Kyselina acetylsalicylova [Czech]
LANORINAL
Levius
Lopac-A-5376
Lopac0_000038
LS-143
Magnecyl
Measurin
Medisyl
MEPRO-ASPIRIN
MEPROBAMATE AND ASPIRIN
METHOCARBAMOL AND ASPIRIN
Micrainin
Micristin
Mixture Name
MLS001055329
MLS001066332
MLS001336045
MLS001336046
NCGC00015067-01
NCGC00015067-02
NCGC00015067-03
NCGC00015067-04
NCGC00015067-05
NCGC00015067-06
NCGC00015067-07
NCGC00015067-08
NCGC00015067-09
NCGC00015067-10
NCGC00015067-11
NCGC00015067-12
NCGC00090977-01
NCGC00090977-02
NCGC00090977-03
NCGC00090977-04
NCGC00090977-05
NCGC00090977-06
NCGC00090977-07
nchem.859-comp6
NCI60_002222
Neuronika
NINDS_000555
Norgesic
NORGESIC FORTE
Novid
NSC 27223
NSC27223
NSC406186
Nu-seals
Nu-Seals Aspirin
O-accetylsalicylic acid
o-Acetoxybenzoic acid
O-Acetylsalicylic acid
o-Carboxyphenyl acetate
ORPHENADRINE CITRATE, ASPIRIN, AND CAFFEINE
ORPHENGESIC
ORPHENGESIC FORTE
OXYCODONE AND ASPIRIN
OXYCODONE AND ASPIRIN (HALF-STRENGTH)
P-A-C Analgesic Tablets
Percodan
Percodan Demi
PERCODAN-DEMI
Persistin
Pharmacin
Phensal
Pirseal
PL-2200
Polopirin
Polopiryna
Pravigard PAC
Premaspin
Propoxyphene Compound 65
PROPOXYPHENE COMPOUND-65
PROPOXYPHENE HCL W/ ASPIRIN AND CAFFEINE
Q-GESIC
R16CO5Y76E [UNII]
Rheumin tabletten
Rheumintabletten
Rhodine
Rhonal
Robaxisal
Ronal
ROXIPRIN
S-211
Salacetin
Salcetogen
Saletin
Salicylic acid acetate
Salicylic acid, acetate
SBB015069
Sine-Off Sinus Medicine Tablets-Aspirin Formula
SK-65 Compound
SMR000059138
Solfrin
Solprin
Solprin acid
Solpyron
Solupsan
Soma Compound
SOMA COMPOUND W/ CODEINE
SP 189
SPBio_001838
SPECTRUM1500130
Spectrum2_001899
Spectrum3_001295
Spectrum4_000099
Spectrum5_000740
Spectrum_001245
Spira-Dine
St. Joseph
St. Joseph Aspirin for Adults
ST075414
STL137674
Supac
Synalgos
Synalgos-DC
TALWIN COMPOUND
Tasprin
Temperal
Triple-sal
UNII R16CO5Y76E
UNII-R16CO5Y76E
UNII=R16CO5Y76E
UNM-0000306102
Vanquish
VICOPRIN
WLN: QVR BOV1
XAXA
Yasta
ZORprin
ATC-Codes:
Side-Effects:
Side-EffectFrequency
anaphylaxis0
nausea0
pruritus0
purpura0
sweating0
thrombocytopenia0
tinnitus0
ulcer0
urticaria0
vertigo0
vomiting0
melena0
leukopenia0
anemia0
angioedema0
asthma0
confusion0
diarrhea0
somnolence0
dyspepsia0
heartburn0
hematemesis0
hypersensitivity0
hearing loss0

Target

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Uniprot ID:PGH2_SHEEP
Synonyms:
COX-2
Cyclooxygenase-2
PGH synthase 2
PGHS-2
PHS II
Prostaglandin G/H synthase 2
Prostaglandin H2 synthase 2
Prostaglandin-endoperoxide synthase 2
EC-Numbers:1.14.99.1
Organism:Ovis aries
Sheep
PDB IDs:-

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
--2400-
--2530-
-->100000-
--660000-
-->5000000-

References: