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Drug-Target Interaction

Drug

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PubChem ID:219099
Structure:
Synonyms:
122883-93-6
2H-Indol-2-one,
2H-Indol-2-one, 5-(2-(4-(1,2-benzisothiazol-3-yl)-1-piperazinyl)ethyl)-6-chloro-1,3-dihydro-, monohydrochloride
C21H21ClN4OS.HCl
CP 88059-1
GEODON
LS-172544
TL8000613
Zeldox
Ziprasidone HCl
Ziprasidone hydrochloride
Ziprasidone hydrochloride [USAN]
Ziprasidone.HCl
Side-Effects:
Side-EffectFrequency
dysarthria1.0
abnormal gait1.0
choreoathetosis1.0
neuropathy1.0
confusion1.0
ataxia1.0
diplopia1.0
flank pain1.0
chills1.0
vertigo1.0
fever1.0
photosensitivity1.0
delirium1.0
hypothermia1.0
amnesia1.0
tremor0.82777774
dyskinesia0.82777774
dyspnea0.44625002
agitation0.41764706
abdominal pain0.41764706
flu syndrome0.41470596
fungal dermatitis0.3671429
myalgia0.3642857
hypertension0.3295455
postural hypotension0.3089412
edema0.30254176
vomiting0.28769237
tachycardia0.28577778
anorexia0.27052632
paresthesia0.23213635
somnolence0.15749998
schizophrenia0.14
lightheadedness0.12
headache0.10958332
dizziness0.08699999
nausea0.08250001
pain0.080000006
paralysis0.071428575
infection0.057777777
constipation0.04578947
dyspepsia0.040833324
abnormal vision0.03785714
asthenia0.032083336
diarrhea0.029473685
anxiety0.026842108
chest pain0.025555555
dry mouth0.024166668
increased salivation0.02222222
rash0.021777775
pharyngitis0.02111111
cough0.02111111
rhinitis0.017368421
insomnia0.012666666
dysphagia0.010624999
dysmenorrhea0.01
sweating0.01
personality disorder0.01
furunculosis0.01
bradycardia0.01
menorrhagia0.009999999
leukopenia0.009999999
leukocytosis0.009999999
albuminuria0.009999999
urinary retention0.009999999
blepharitis0.009999999
conjunctivitis0.009999999
impotence0.009999999
metrorrhagia0.009999999
angina pectoris0.009999999
tenosynovitis0.009999999
alopecia0.009999999
eczema0.009999999
polyuria0.009999999
tinnitus0.009999999
atrial fibrillation0.009999999
amenorrhea0.009999999
anemia0.009999999
cataract0.009999999
dehydration0.009999999
exfoliative dermatitis0.009999999
hyperglycemia0.009999999
hypercholesteremia0.009999999
glycosuria0.009999999
lactic dehydrogenase increased0.009999999
pneumonia0.009999999
hematuria0.009999999
alkaline phosphatase increased0.009999999
eosinophilia0.009999999
ecchymosis0.009999999
rectal hemorrhage0.009999999
peripheral edema0.009999999
lymphadenopathy0.009999999
contact dermatitis0.009999999
dry eyes0.009999999
epistaxis0.009999999
photophobia0.009999999
hypokalemia0.009999999
urticaria0.008874999
sexual dysfunction0.0054999995
back pain0.0050
tooth disorder0.0050
psychosis0.0050
priapism0.0046363636
allergic reaction0.0010
thrombophlebitis0.0010
hyperchloremia0.0010
thrombocytopenia0.0010
galactorrhea0.0010
thyroiditis0.0010
torticollis0.0010
tardive dyskinesia0.0010
hyperuricemia0.0010
thrombocythemia0.0010
vascular disorders0.0010
uterine hemorrhage0.0010
urinary incontinence0.0010
vaginal hemorrhage0.0010
hypomagnesemia0.0010
deep thrombophlebitis0.0010
hypochloremia0.0010
syncope0.0010
respiratory alkalosis0.0010
gynecomastia0.0010
cardiac disorders0.0010
cardiomegaly0.0010
hematemesis0.0010
hemorrhage0.0010
hepatitis0.0010
hepatomegaly0.0010
hyperkalemia0.0010
hyperlipemia0.0010
hyperthyroidism0.0010
gout0.0010
gum hemorrhage0.0010
hypochromic anemia0.0010
angioedema0.0010
av block0.0010
breast disorders0.0010
bundle branch block0.0010
allergic dermatitis0.0010
cerebral infarct0.0010
enuresis0.0010
fatty liver0.0010
fecal impaction0.0010
hypocalcemia0.0010
hypoglycemia0.0010
hyponatremia0.0010
myopathy0.0010
myocarditis0.0010
nocturia0.0010
nystagmus0.0010
phlebitis0.0010
hemoptysis0.0010
polycythemia0.0010
pulmonary embolus0.0010
visual field defect0.0010
melena0.0010
serotonin syndrome0.0010
hypothyroidism0.0010
jaundice0.0010
keratitis0.0010
keratoconjunctivitis0.0010
leukoplakia of mouth0.0010
lymphedema0.0010
lymphocytosis0.0010
cerebrovascular accident0.0010
weight gain0
weight loss0
upper respiratory tract infection0
arthralgia0
spasm0

Target

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Uniprot ID:5HT2A_HUMAN
Synonyms:
5-HT-2
5-HT-2A
5-hydroxytryptamine receptor 2A
Serotonin receptor 2A
EC-Numbers:-
Organism:Homo sapiens
Human
PDB IDs:-

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
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References: