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Drug-Target Interaction

Drug

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PubChem ID:2162
Structure:
Synonyms:
3,5-Pyridinedicarboxylic acid,
3,5-Pyridinedicarboxylic acid, 2-((2-aminoethoxy)methyl)-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-, 3-ethyl 5-methyl ester
3-ethyl 5-methyl 2-{[(2-aminoethyl)oxy]methyl}-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
3-Ethyl-5-methyl ( -)-2-((2-aminoethoxy)methyl)-4-(2-chlorphenyl)-1,4-dihydro-6-methyl-3,5-pyridindicarboxylat
3-Ethyl-5-methyl ( -)-2-((2-aminoethoxymethyl)-4-(o-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate
3-Ethyl-5-methyl (.+/-.)-2-[(2-aminoethoxy)methyl]-4-(o-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate
88150-42-9
88150-47-4
Ambap6294
Amlocard
Amlodipine
Amlodipine (INN)
AMLODIPINE BASE
Amlodipine Benzenesulfonate
Amlodipine Besilate
Amlodipine Besylate
Amlodipine Free Base
Amlodipine [INN:BAN]
Amlodipine, Istin, Norvasc, Caduet
Amlodipino
Amlodipino [Spanish]
Amlodipinum
Amlodipinum [Latin]
Amlodis
Amlopres
BSPBio_002727
C06825
CHEBI:2668
Coroval
CPD000469198
D07450
DB00381
Exforge
Intervask
KBio3_001947
KBioGR_001643
Lipinox
Lotrel
LS-131183
Mixture Name
MLS001401409
NCGC00165957-01
NCGC00165957-02
NCGC00165957-03
Norvasc
Norvasc (TN)
O3-ethyl O5-methyl 2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
Racemic Amlodipine
SAM001246705
SMR000469198
SPBio_000351
Spectrum2_000486
Spectrum3_001004
Spectrum4_001132
Spectrum5_001550
UK-4834011
ATC-Codes:
Side-Effects:
Side-EffectFrequency
edema0.100999996
flushing0.030000001
palpitations0.0235
somnolence0.014500001
coronary artery disease0.0010
peripheral vascular disease0.0010
chronic obstructive pulmonary disease0.0010
congestive heart failure0.0010
hepatitis0.0010
diabetes mellitus0.0010
jaundice0.0010
gynecomastia0.0010
syncope0
tachycardia0
thrombocytopenia0
tinnitus0
tremor0
stevens - johnson syndrome0
pancreatitis0
paresthesia0
peripheral neuropathy0
polyuria0
pruritus0
sexual dysfunction0
purpura0
rhinitis0
pain0
erythema0
urticaria0
muscle weakness0
eye pain0
dry skin0
malaise0
myalgia0
bradycardia0
urinary frequency0
increased sweating0
insomnia0
migraine0
peripheral edema0
apathy0
vasculitis0
ventricular tachycardia0
vertigo0
abnormal vision0
vomiting0
weight gain0
weight loss0
dry mouth0
agitation0
allergic reaction0
nocturia0
abdominal pain0
back pain0
chest pain0
conjunctivitis0
constipation0
cough0
dysphagia0
depersonalization0
dermatitis0
atrial fibrillation0
ataxia0
alopecia0
amnesia0
angioedema0
anorexia0
anxiety0
arrhythmia0
arthralgia0
asthenia0
diarrhea0
diplopia0
dizziness0
postural hypotension0
ischemia0
arthrosis0
leukopenia0
gastritis0
muscle cramps0
myocardial infarction0
nausea0
hyperglycemia0
headache0
dyspepsia0
dyspnea0
dysuria0
epistaxis0
erythema multiforme0
rash0
fatigue0
flatulence0
nervousness0

Target

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Uniprot ID:CP1A1_HUMAN
Synonyms:
CYPIA1
Cytochrome P450 1A1
P450 form 6
P450-C
P450-P1
EC-Numbers:1.14.14.1
Organism:Homo sapiens
Human
PDB IDs:-

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
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References: