Home
Drugs
Targets
Pathways
Ontologies
Cyp450s
Adv.search
Help/FAQ

Drug-Target Interaction

Drug

show drug details
PubChem ID:2160
Structure:
Synonyms:
1-Propanamine, 3-(10,11-dihydro-5H-dibenzo(a,d)cyclohepten-5-ylidene)-N,N-dimethyl-
1-propanamine, 3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N,N-dimethyl-
10,11-Dihydro-5-(gamma-dimethylaminopropylidene)-5H-dibenzo(a,d)cyclohepte
10,11-Dihydro-5-(gamma-dimethylaminopropylidene)-5H-dibenzo(a,d)cycloheptene
10,11-dihydro-5-(gamma-dimethylaminopropylidene)-5H-dibenzo[a,d]cycloheptene
10,11-dihydro-N,N-dimethl-5H-dibenzo[a,d]cycloheptene-(delta(5, gamma))-propylamine
10,11-dihydro-N,N-dimethyl-5H-dibenzo(a,d)heptalene-Delta(5),gamma-propylamine
10,11-Dihydro-N,N-dimethyl-5H-dibenzo(a,d)heptalene-delta(sup 5),gamma-propylamine
17086-03-2
3-(10,11-Dihydro-5H-dibenzo(a,d)cyclohepten-5-yliden)-N,N-dimethylpropylamin
3-(10,11-Dihydro-5H-dibenzo(a,d)cyclohepten-5-ylidene)-N,N-dimethyl-1-propanamine
3-(10,11-dihydro-5H-dibenzo-[a,d]cyclohepten-5-ylidene)-N,N-dimethyl-1-propanamine
3-(10,11-Dihydro-5H-dibenzo-[a,d]cyclohepten-5-ylidene)-N,N-dimethyl-1-propanamine, hydrochloride
3-(10,11-Dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N,N-dimethyl-1-propanamine
3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N,N-dimethylpropan-1-amine
3-(10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-ylidene)-N,N-dimethylpropan-1-amine
30227-34-0
5-(3'-Dimethylaminopropylidene)-dibenzo-(a,d)(1,4)-cycloheptadiene
5-(3'-Dimethylaminopropylidene)-dibenzo-[a,d][1,4]-cycloheptadiene
5-(3-dimethylaminopropylidene)-10,11-dihydro-5H-dibenzo(a,d)cycloheptatriene
5-(3-Dimethylaminopropylidene)-10,11-dihydro-5H-dibenzo(a,d)cycloheptene
5-(3-Dimethylaminopropylidene)-5H-dibenzo[a,d]-10,11-dihydrocycloheptene
5-(3-dimethylaminopropylidene)dibenzo[a,d][1,4]-cycloheptadiene
5-(gamma-Dimethylaminopropylidene)-10,11-dihydro-5H-dibenzo(a,d)cycloheptene
5-(gamma-Dimethylaminopropylidene)-5H-dibenzo(a,d)(1,4)cycloheptadiene
5-(gamma-Dimethylaminopropylidene)-5H-dibenzo[a,d]10,11-dihydrocycloheptene
5-(gamma-dimethylaminopropylidene)-5H-dibenzo[a,d][1,4]cycloheptadiene
5-(gamma-Dimethylaminopropylidine)-5H-dibenzo(a,d)(1,4)cycloheptadiene
50-48-6
549-18-8
549-18-8 (HCL)
5H-Dibenzo(a,d)cycloheptene-delta(sup 5),gamma-propylamine, 10,11-dihydro-N,N-dimethyl-
5H-Dibenzo(a,d)cycloheptene-delta5,gamma-propylamine, 10,11-dihydro-N,N-dimethyl-
5H-Dibenzo[a,d]cycloheptene-.delta.5,.gamma.-propylamine, 10,11-dihydro-N,N-dimethyl-
5H-Dibenzo[a,d]cycloheptene-Delta5,gamma-propylamine, 10,11-dihydro-N,N-dimethyl- (6CI,8CI) 5-(gamma-Dimethylaminopropylidene)-10,11-dihydro-5H-dibenzo[a,d]cycloheptene
AB00514631
Adepress
Adepril
AIDS-001620
AIDS001620
Amitril
Amitriprolidine
Amitriptilina [INN-Spanish]
Amitriptilina [Italian]
Amitriptylin
Amitriptylin [German]
Amitriptyline
Amitriptyline (INN)
Amitriptyline HCL
Amitriptyline Hydrochloride
Amitriptyline [INN:BAN]
Amitriptylinum [INN-Latin]
Amitryptiline
Amitryptyline
Amytriptiline
Amytriptylin
Antihistamine compound
BAS 00269727
BPBio1_000317
BRN 2217885
BSPBio_000287
BSPBio_001836
C06824
C20H23N
CAS-549-18-8
CCRIS 9174
CHEBI:2666
cMAP_000001
D07448
Damilan
Damilen
Damitriptyline
DB00321
DivK1c_000766
EINECS 200-041-6
Elavil
Flavyl
HSDB 3007
IDI1_000766
KBio1_000766
KBio2_000424
KBio2_002261
KBio2_002992
KBio2_004829
KBio2_005560
KBio2_007397
KBio3_001336
KBio3_002741
KBioGR_000592
KBioGR_002261
KBioSS_000424
KBioSS_002262
Lantron
Laroxil
Laroxyl
Laroxyl (TN)
Lentizol
Lopac-A-8404
Lopac0_000112
LS-60747
MK 230
N 750
NCGC00015095-01
NCGC00015095-02
NCGC00015095-03
NCGC00024433-04
NCGC00024433-05
NINDS_000766
NSC169910 (HCL)
Oprea1_479304
PDSP1_001564
PDSP2_001548
Prestwick0_000074
Prestwick1_000074
Prestwick2_000074
Prestwick3_000074
Proheptadiene
Redomex
Ro 4-1575
Saroten
Sarotex
Seroten
SPBio_000082
SPBio_002208
Spectrum2_000101
Spectrum3_000298
Spectrum4_000146
Spectrum5_000806
Spectrum_000044
ST5220564
Sylvemid
Triptanol
Triptilin
Triptisol
Tryptanol
Tryptizol
[3-(10,11-Dihydro-dibenzo[a,d]cyclohepten-5-ylidene)-propyl]-dimethyl-amine
ATC-Codes:
Side-Effects:
Side-EffectFrequency
insomnia0.0010
tachycardia0.0010
syncope0.0010
swelling0.0010
perspiration0.0010
stroke0.0010
stomatitis0.0010
seizures0.0010
purpura0.0010
peripheral neuropathy0.0010
paresthesias0.0010
weakness0.0010
paralytic ileus0.0010
palpitation0.0010
numbness0.0010
nightmares0.0010
nausea0.0010
thrombocytopenia0.0010
tinnitus0.0010
tremor0.0010
cardiomyopathy0.0010
diaphoresis0.0010
tardive dyskinesia0.0010
urinary frequency0.0010
blurred vision0.0010
testicular swelling0.0010
galactorrhea0.0010
malaise0.0010
positive ana0.0010
restlessness0.0010
hepatic failure0.0010
urinary retention0.0010
dry mouth0.0010
weight gain0.0010
vomiting0.0010
urticaria0.0010
myocardial infarction0.0010
serotonin syndrome0.0010
eosinophilia0.0010
edema0.0010
dysarthria0.0010
drowsiness0.0010
dizziness0.0010
diarrhea0.0010
decreased libido0.0010
constipation0.0010
confusional states0.0010
coma0.0010
ataxia0.0010
arthritis0.0010
arrhythmias0.0010
anxiety0.0010
anorexia0.0010
alopecia0.0010
skin rash0.0010
fatigue0.0010
lupus0.0010
leukopenia0.0010
jaundice0.0010
inappropriate adh0.0010
impotence0.0010
orthostatic hypotension0.0010
hypotension0.0010
breast enlargement0.0010
hypertension0.0010
fever0.0010
gynecomastia0.0010
hallucinations0.0010
headache0.0010
heart block0.0010
hepatitis0.0010
agranulocytosis0.0010
irritability0
excitement0
delusions0

Target

show target details
Uniprot ID:CP2C9_HUMAN
Synonyms:
(R)-limonene 6-monooxygenase
(S)-limonene 6-monooxygenase
(S)-limonene 7-monooxygenase
CYPIIC9
Cytochrome P450 2C9
P-450MP
P450 MP-4/MP-8
P450 PB-1
S-mephenytoin 4-hydroxylase
EC-Numbers:1.14.13.48
1.14.13.49
1.14.13.80
Organism:Homo sapiens
Human
PDB IDs:1OG2 1OG5 1R9O
Structure:
1R9O

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
----

References: