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Drug-Target Interaction

Drug

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PubChem ID:2146
Structure:
Synonyms:
1937-19-5
1937-19-5 (hydrochloride)
2-aminoguanidine
2-azanylguanidine
79-17-4
AC1L1D0U
AC1Q4T1I
AGU
AIDS-030897
AIDS030897
Aminate base
Aminoguanidine
Aminoguanidine (AG)
Aminoguanidine hydrochloride
Aminoguanidine, Hemisulfate
AR-1J1440
CCG-204198
CCRIS 3511
CHEBI:40618
CHEMBL225304
DB02533
EINECS 201-183-1
GER-11
GUANIDINE, AMINO-
Guanyl hydrazine
guanylhydrazine
HSCI1_000380
Hydrazinecarboximidamide
Hydrazinecarboximidamide (9CI)
Imino semicarbazide
Lopac-A-7009
Lopac-A-8835
Lopac0_000050
Lopac0_000103
LS-73211
MDL-201228
Monoaminoguanidine
NCGC00015082-01
NCGC00015082-02
NCGC00015082-03
NCGC00015082-04
NCGC00015082-05
NCGC00015082-06
NCGC00015082-07
NCGC00024791-01
NCGC00024791-02
NCGC00024791-03
Pimagedine
Pimagedine [INN]
Tocris-0787
YM-585

Target

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Uniprot ID:NOS3_HUMAN
Synonyms:
cNOS
Constitutive NOS
EC-NOS
Endothelial NOS
eNOS
Nitric oxide synthase, endothelial
NOS type III
NOSIII
EC-Numbers:1.14.13.39
Organism:Homo sapiens
Human
PDB IDs:1M9J 1M9K 1M9M 1M9Q 1M9R 3EAH 3NOS
Structure:
3NOS

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
--72000-
--100000-
--500000-

References: