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Drug-Target Interaction

Drug

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PubChem ID:2146
Structure:
Synonyms:
1937-19-5
1937-19-5 (hydrochloride)
2-aminoguanidine
2-azanylguanidine
79-17-4
AC1L1D0U
AC1Q4T1I
AGU
AIDS-030897
AIDS030897
Aminate base
Aminoguanidine
Aminoguanidine (AG)
Aminoguanidine hydrochloride
Aminoguanidine, Hemisulfate
AR-1J1440
CCG-204198
CCRIS 3511
CHEBI:40618
CHEMBL225304
DB02533
EINECS 201-183-1
GER-11
GUANIDINE, AMINO-
Guanyl hydrazine
guanylhydrazine
HSCI1_000380
Hydrazinecarboximidamide
Hydrazinecarboximidamide (9CI)
Imino semicarbazide
Lopac-A-7009
Lopac-A-8835
Lopac0_000050
Lopac0_000103
LS-73211
MDL-201228
Monoaminoguanidine
NCGC00015082-01
NCGC00015082-02
NCGC00015082-03
NCGC00015082-04
NCGC00015082-05
NCGC00015082-06
NCGC00015082-07
NCGC00024791-01
NCGC00024791-02
NCGC00024791-03
Pimagedine
Pimagedine [INN]
Tocris-0787
YM-585

Target

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Uniprot ID:NOS2_MOUSE
Synonyms:
Inducible NO synthase
Inducible NOS
iNOS
MAC-NOS
Macrophage NOS
Nitric oxide synthase, inducible
NOS type II
EC-Numbers:1.14.13.39
Organism:Mouse
Mus musculus
PDB IDs:1DD7 1DF1 1DWV 1DWW 1DWX 1JWJ 1JWK 1M8D 1M8E 1M8H 1M8I 1M9T 1N2N 1NOC 1NOD 1NOS 1QOM 1QW4 1QW5 1R35 1VAF 2BHJ 2NOD 2NOS 2ORO 2ORP 2ORQ 2ORR 2ORS 2ORT 3DWJ 3E65 3E67 3E68 3E6L 3E6N 3E6O 3E6T 3E7I 3E7M 3E7T 3EAI 3EBD 3EBF 3NOD
Structure:
3NOD

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
----
--9000-

References: