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Drug-Target Interaction

Drug

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PubChem ID:2146
Structure:
Synonyms:
1937-19-5
1937-19-5 (hydrochloride)
2-aminoguanidine
2-azanylguanidine
79-17-4
AC1L1D0U
AC1Q4T1I
AGU
AIDS-030897
AIDS030897
Aminate base
Aminoguanidine
Aminoguanidine (AG)
Aminoguanidine hydrochloride
Aminoguanidine, Hemisulfate
AR-1J1440
CCG-204198
CCRIS 3511
CHEBI:40618
CHEMBL225304
DB02533
EINECS 201-183-1
GER-11
GUANIDINE, AMINO-
Guanyl hydrazine
guanylhydrazine
HSCI1_000380
Hydrazinecarboximidamide
Hydrazinecarboximidamide (9CI)
Imino semicarbazide
Lopac-A-7009
Lopac-A-8835
Lopac0_000050
Lopac0_000103
LS-73211
MDL-201228
Monoaminoguanidine
NCGC00015082-01
NCGC00015082-02
NCGC00015082-03
NCGC00015082-04
NCGC00015082-05
NCGC00015082-06
NCGC00015082-07
NCGC00024791-01
NCGC00024791-02
NCGC00024791-03
Pimagedine
Pimagedine [INN]
Tocris-0787
YM-585

Target

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Uniprot ID:NOS1_RAT
Synonyms:
BNOS
Constitutive NOS
N-NOS
NC-NOS
Neuronal NOS
Nitric oxide synthase, brain
nNOS
NOS type I
EC-Numbers:1.14.13.39
Organism:Rat
Rattus norvegicus
PDB IDs:1B8Q 1F20 1K2R 1K2S 1K2T 1K2U 1LZX 1LZZ 1M00 1MMV 1MMW 1OM4 1OM5 1P6H 1P6I 1P6J 1P6K 1QAU 1QAV 1QW6 1QWC 1RS6 1RS7 1TLL 1VAG 1ZVI 1ZVL 1ZZQ 1ZZR 1ZZU 2G6H 2G6I 2G6J 2G6K 2G6L 2G6M 2G6N 2HX3 2HX4 3B3M 3B3N 3B3O 3B3P 3DQR
Structure:
3DQR

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
--6000-

References: