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Drug-Target Interaction

Drug

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PubChem ID:2145
Structure:
Synonyms:
( inverted question mark)-p-Aminoglutethimide
(+-)-3-(p-Aminophenyl)-3-ethyl-2,6-piperidinedione
(+/-)-p-AMINOGLUTETHIMIDE
(?)-p-Aminoglutethimide
.alpha.-(p-Aminophenyl)-.alpha.-ethylglutarimide
125-84-8
2,6-Piperidinedione, 3-(4-aminophenyl)-3-ethyl-
2-(p-Aminophenyl)-2-ethylglutarimide
3-(4-Aminophenyl)-3-ethyl-2,6-piperidindion
3-(4-Aminophenyl)-3-ethyl-2,6-piperidinedione
3-(4-aminophenyl)-3-ethylpiperidine-2,6-dione
3-(p-Aminophenyl)-3-ethylpiperidine-2,6-dione
3-Ethyl-3-(p-aminophenyl)-2,6-dioxopiperidine
5-22-13-00297 (Beilstein Handbook Reference)
A 9657
A1947
A9657_SIGMA
AB00051935
AC-12456
AC1L1D0R
AC1Q2SPJ
AG-1
AKOS004120070
alpha-(p-Aminophenyl)-alpha-ethylglutarimide
Aminoglutethimide
aminoglutethimide (AG)
Aminoglutethimide (USP/INN)
Aminoglutethimide [BAN:INN]
Aminoglutethimide [INN:BAN]
Aminoglutethimidum
Aminoglutethimidum [INN-Latin]
Aminoglutetimida
Aminoglutetimida [INN-Spanish]
Ba 16038
Ba-16038
BB_SC-1153
BPBio1_000032
BRD-A25234499-001-05-0
BRN 0210656
BSPBio_000028
BSPBio_001832
C 16038-BA
C07617
C13H16N2O2
CCG-38911
CCRIS 7562
CHEBI:2654
CHEMBL488
Ciba Vision Brand of Aminoglutethimide
CPD-10532
CPD000326785
Cytadren
Cytadren (TN)
D000616
D00574
DB00357
DivK1c_000884
DL-AMINOGLUTETHIMIDE
EINECS 204-756-4
Elipten
EU-0100124
Glutarimide, 2-(p-aminophenyl)-2-ethyl-
Glutethimide, para-amino
HMS1568B10
HMS1920C09
HMS2090I05
HMS2091I09
HMS2095B10
HMS2231M19
HMS3259H10
HMS3260I10
HMS502M06
HSDB 7494
IDI1_000884
KBio1_000884
KBio2_000400
KBio2_002968
KBio2_005536
KBio3_001332
KBioGR_000588
KBioSS_000400
Lopac0_000124
LS-72014
MLS000859924
MLS001213216
NCGC00015110-02
NCGC00015110-03
NCGC00015110-04
NCGC00015110-05
NCGC00015110-06
NCGC00015110-07
NCGC00093615-01
NCGC00093615-02
NCGC00093615-03
NCGC00093615-04
NCGC00093615-05
NCI60_002900
NINDS_000884
Novartis Brand of Aminoglutethimide
NSC330915
Orimeten
p-Aminoglutethimide
Prestwick0_000244
Prestwick1_000244
Prestwick2_000244
Prestwick3_000244
Prestwick_243
S1672_Selleck
SAM002589964
SBB000711
SMP1_000017
SMR000326785
SPBio_000046
SPBio_002247
SPECTRUM1500115
Spectrum2_000093
Spectrum3_000296
Spectrum4_000144
Spectrum5_000802
Spectrum_000040
STK802074
UNII-0O54ZQ14I9
VU0243029-3
ATC-Codes:
Side-Effects:
Side-EffectFrequency
rash0
vomiting0
somnolence0
allergic alveolitis0
orthostasis0
pancytopenia0
hirsutism0
nausea0
anorexia0
adrenal insufficiency0
myalgia0
hypotension0
leukopenia0
cancer0
tachycardia0
urticaria0
fever0
hypersensitivity0
neutropenia0
dizziness0
pruritus0
hemolytic anemia0
agranulocytosis0
goiter0
anemia0
hypothyroidism0
masculinization0
headache0

Target

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Uniprot ID:C11B2_HUMAN
Synonyms:
ALDOS
Aldosterone synthase
Aldosterone-synthesizing enzyme
CYPXIB2
Cytochrome P450 11B2, mitochondrial
P-450Aldo
P-450C18
Steroid 18-hydroxylase
EC-Numbers:1.14.15.4
1.14.15.5
Organism:Homo sapiens
Human
PDB IDs:-

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
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References: