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Drug-Target Interaction

Drug

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PubChem ID:214
Structure:
Synonyms:
(-)-Prostaglandin E1
(1R,2R,3R)-3-Hydroxy-2-[(E)-(3S)-3-hydroxy-1-octenyl]-5-oxocynlopentanehep
(1R,2R,3R)-3-Hydroxy-2-[(E)-(3S)-3-hydroxy-1-octenyl]-5-oxocynlopentaneheptanoic acid
11.alpha.,15.alpha.-Dihydroxy-9-oxo-13-trans-prostenoic acid
11alpha,13E,15S]-11,15-Dihydroxy-9-oxoprosta-13-en-1-oic acid
7-[3-hydroxy-2-(3-hydroxyoct-1-enyl)-5-oxocyclopentyl]heptanoic acid
745-65-3
AC1L18QG
Alprostadil
CID214
Cyclopentaneheptanoic acid, 3-hydroxy-2-(3-hydroxy-1-octenyl)-5-oxo-
Cyclopentaneheptanoic acid, 3-hydroxy-2-(3-hydroxy-1-octenyl)-5-oxo-, (+)-
Cyclopentaneheptanoic acid, 3-hydroxy-2-(3-hydroxy-1-octenyl)-5-oxo-, (-)-
l-Prostaglandin E1
NSC165559
PGE1
Prost-13-en-1-oic acid, 11,15-dihydroxy-9-oxo-, (11.alpha.,13E,15S)-
Prostaglandin E1
U 10136
U-10,136
Side-Effects:
Side-EffectFrequency
penile pain0.1875
upper respiratory infection0.04
spotting0.030000001
bleeding0.030000001
testicular pain0.030000001
flu0.026666665
infection0.024999999
headache0.023333333
hematoma0.02
pain0.02
hypertension0.02
sinusitis0.02
fibrosis0.02
dizziness0.015
rhinitis0.015
pelvic pain0.015
back pain0.013333333
nasal congestion0.01
cough0.01
spasm0
increased sweating0
urinary frequency0
dental abscess0
urinary urgency0
shock0
seizures0
renal failure0
pruritus0
prostatitis0
swelling0
syncope0
tachycardia0
peripheral vascular disorder0
dry mouth0
burning sensation0
wheezing0
intracranial hemorrhage0
ventricular fibrillation0
urinary tract infection0
regurgitation0
sepsis0
erythema0
thrombocytopenia0
second degree heart block0
bradycardia0
supraventricular tachycardia0
priapism0
supraventricular extrasystoles0
pneumothorax0
cardiac arrest0
flushing0
fever0
rash0
edema0
ecchymosis0
dyspepsia0
abdominal pain0
diarrhea0
bronchitis0
balanitis0
asthenia0
apnea0
hypochromic anemia0
congestive heart failure0
hematuria0
bilirubinemia0
phimosis0
pharyngitis0
peritonitis0
numbness0
tumor0
nausea0
leg pain0
leg cramps0
hypothermia0
hypotension0
hypokalemia0
hypoglycemia0
hyperkalemia0
hypercarbia0
anemia0

Target

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Uniprot ID:PE2R2_HUMAN
Synonyms:
PGE receptor, EP2 subtype
Prostaglandin E2 receptor EP2 subtype
Prostanoid EP2 receptor
EC-Numbers:-
Organism:Homo sapiens
Human
PDB IDs:-

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
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References: