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Drug-Target Interaction

Drug

show drug details
PubChem ID:2130
Structure:
Synonyms:
1-Adamantamine
1-Adamantanamine
1-Adamantanamine (8CI)
1-Adamantylamine
1-Aminoadamantane
1-Aminotricyclo(3.3.1.1(sup 3,7))decane
138576_ALDRICH
665-66-7
665-66-7 (HCL)
665-66-7 (hydrochloride)
768-94-5
768-94-5 (FREE BASE)
AB00514655
AC-11992
AC1L1CZI
AC1Q4UAF
AC1Q5396
Adamantamine
adamantan-1-amine
adamantan-1-ylamine
Adamantanamine
ADAMANTANE,1-AMINO
adamantanylamine
Adamantylamine
AG-H-07057
AIDS-001627
AIDS001627
AKOS000113994
AKOS000119324
Amant
Amantadina
Amantadina [INN-Spanish]
Amantadine
Amantadine (INN)
Amantadine Base
Amantadine HCL
Amantadine hydrochloride
Amantadine Sulfate
Amantadine [INN:BAN]
Amantadinum
Amantadinum [INN-Latin]
Amantidine
Ambap3574
Ambap768-94-5
Aminoadamantane
BBL004977
BIA4304
BIDD:GT0757
Bio-0821
BPBio1_000368
BRN 2204333
BSPBio_000334
BSPBio_001570
BSPBio_001822
C06818
C10H17N
CCG-204100
CHEBI:2618
CHEMBL19601
CHEMBL660
D07441
DB00915
DivK1c_000815
EINECS 212-201-2
Endantadine
Exp-105-1
Gen-Amantadine
HMS1791O12
HMS1989O12
HSDB 3202
I14-1101
IDI1_000815
KBio1_000815
KBio2_000390
KBio2_002958
KBio2_005526
KBio3_001322
KBioGR_000548
KBioSS_000390
L000868
Lopac-A-1260
Lopac0_000004
LS-157049
Mantadine
Midantan
MolPort-015-137-498
NCGC00015036-01
NCGC00015036-02
NCGC00015036-03
NCGC00015036-04
NCGC00015036-05
NCGC00015036-06
NCGC00015036-07
NCGC00015036-08
NCGC00015036-09
NCGC00162039-01
NCGC00162039-02
NCGC00162039-03
NCGC00162039-04
NCGC00179597-01
NCIOpen2_001059
NINDS_000815
NSC 341865
NSC341865
NSC341865 (FREE BASE)
NSC83653
NSC83653 (HCL)
Oprea1_248648
OR14310
Pk-merz
Prestwick0_000407
Prestwick1_000407
Prestwick2_000407
Prestwick3_000407
SPBio_000002
SPBio_002273
Spectrum2_000081
Spectrum3_000291
Spectrum4_000134
Spectrum5_000772
Spectrum_000030
ST097860
ST5202969
STK298781
Symadine
Symmetrel
TCMDC-125869
TL8005280
Tricyclo(3.3.1.1(3,7))-decan-1-amine
Tricyclo(3.3.1.1(sup 3,7))decan-1-amine
Tricyclo(3.3.1.1(sup 3.7))decan-1-amine
Tricyclo(3.3.1.13,7)decan-1-amine
tricyclo[3.3.1.1(3,7)]decan-1-amine
tricyclo[3.3.1.1(3,7)]decan-1-ylamine
tricyclo[3.3.1.1(3,7)]decane-1-amine
Tricyclo[3.3.1.1(sup3,7)]decan-1-amine
Tricyclo[3.3.1.1^3,7]decan-1-amine
tricyclo[3.3.1.1~3,7~]decan-1-amine
UNII-BF4C9Z1J53
Viregyt
Wiregyt
WLN: L66 B6 A B- C 1B ITJ BZ
ATC-Codes:
Side-Effects:
Side-EffectFrequency
coma0.0010
delirium0.0010
pruritus0.0010
agitation0.0010
pulmonary edema0.0010
cardiac arrest0.0010
edema0.0010
tremor0.0010
tachycardia0.0010
hypotension0.0010
fever0.0010
dysphagia0.0010
paresthesia0.0010
anaphylactic reactions0.0010
respiratory failure0.0010
anxiety0.0010
arrhythmias0.0010
hallucinations0.0010
leukocytosis0.0010
allergic reactions0.0010
diaphoresis0.0010
keratitis0.0010
psychosis0
weakness0
neutropenia0
seizures0
vomiting0
peripheral edema0
insomnia0
manic0
nerve palsy0
lightheadedness0
agranulocytosis0
stupor0
urinary retention0
dry mouth0
nervousness0
nausea0
diarrhea0
dermatitis0
delusions0
decreased libido0
corneal opacity0
constipation0
confusion0
ataxia0
anorexia0
dizziness0
somnolence0
dyspnea0
leukopenia0
irritability0
postural hypotension0
fatigue0
hypertension0
congestive heart failure0
headache0
rash0
euphoria0
amnesia0

Target

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Uniprot ID:NMD3B_HUMAN
Synonyms:
Glutamate [NMDA] receptor subunit 3B
N-methyl-D-aspartate receptor subtype NR3B
NMDAR3B
NR3B
EC-Numbers:-
Organism:Homo sapiens
Human
PDB IDs:-

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
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References: