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Drug-Target Interaction

Drug

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PubChem ID:2099
Structure:
Synonyms:
122852-42-0
1H-Pyrido(4,3-b)indol-1-one, 2,3,4,5-tetrahydro-5-methyl-2-((5-methyl-1H-imidazol-4-yl)methyl)-
2,3,4,5-Tetrahydro-5-methyl-2-((5-methyl-1H-imidazol-4-yl)methyl)-1H-pyrid
2,3,4,5-Tetrahydro-5-methyl-2-((5-methyl-1H-imidazol-4-yl)methyl)-1H-pyrido(4,3-b)indol-1-one
5-methyl-2-[(5-methyl-1H-imidazol-4-yl)methyl]-3,4-dihydropyrido[4,3-b]indol-1-one
Alosetron
Alosetron (INN)
Alosetron HCl
CHEBI:253342
D07129
DB00969
GR 68755
Lotronex
LS-187763
NCGC00167528-01
ZINC13537284
ATC-Codes:
Side-Effects:
Side-EffectFrequency
constipation0.110444434
nausea0.056
pain0.040769227
regurgitation0.02
abdominal distention0.015999999
hemorrhoids0.015999999
urticaria0.01
sweating0.01
spasms0.01
hyposalivation0.01
cramps0.01
malaise0.01
urinary frequency0.01
fatigue0.01
anxiety0.01
ischemic colitis0.005999999
fungal infections0.0010
pituitary hypofunction0.0010
fecal occult blood0.0010
proctitis0.0010
muscle pain0.0010
tremors0.0010
ulceration0.0010
light sensitivity0.0010
ischemia0.0010
intussusception0.0010
alopecia0.0010
cholecystitis0.0010
colitis0.0010
ulcerative colitis0.0010
bladder inflammation0.0010
diverticulitis0.0010
abuse0.0010
rash0.0010
confusion0.0010
gastritis0.0010
infections0.0010
hypoglycemia0.0010
hyperglycemia0.0010
hemorrhage0.0010
hematomas0.0010
headache0.0010
gastroenteritis0.0010
bone pain0
eczema0
arrhythmia0
jaundice0
nail disorder0
elevated blood pressure0
dermatitis0
hepatitis0
laryngitis0
folliculitis0
acne0
polyuria0

Target

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Uniprot ID:CP2C9_HUMAN
Synonyms:
(R)-limonene 6-monooxygenase
(S)-limonene 6-monooxygenase
(S)-limonene 7-monooxygenase
CYPIIC9
Cytochrome P450 2C9
P-450MP
P450 MP-4/MP-8
P450 PB-1
S-mephenytoin 4-hydroxylase
EC-Numbers:1.14.13.48
1.14.13.49
1.14.13.80
Organism:Homo sapiens
Human
PDB IDs:1OG2 1OG5 1R9O
Structure:
1R9O

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
----
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References: