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Drug-Target Interaction

Drug

show drug details
PubChem ID:1775
Structure:
Synonyms:
"epasmir ""5"""
"fenidantoin ""s"""
125-59-7
2,4-Imidazolidinedione, 5,5-diphenyl-
2,4-Imidazolidinedione, 5,5-diphenyl- (9CI)
2-hydroxy-5,5-diphenyl-3,5-dihydro-4H-imidazol-4-one
5,5-di(phenyl)imidazolidine-2,4-dione
5,5-Diphenyl-2,4-imidazolidinedione
5,5-Diphenyl-imidazolidine-2,4-dione
5,5-Diphenylhydantoin
5,5-Diphenylhydantoin (IUPAC)
5,5-Diphenylhydantoin (phenytoin)
5,5-Diphenylimidazolidin-2,4-dione
5,5-diphenylimidazolidine-2,4-dione
5,5-Dwufenylohydantoina
5,5-Dwufenylohydantoina [Polish]
57-41-0
630-93-3 (SODIUM SALT)
AI3-52498
AIDS-000219
AIDS000219
Aleviatin
Antisacer
Auranile
BAS 00281572
BSPBio_001437
C07443
C15H12N2O2
Causoin
CCRIS 515
CHEBI:8107
citrullamon
citrulliamon
Comital
Comitoina
component of Mebroin
Convul
D00512
D4007_SIGMA
Danten
Dantinal
Dantoinal
Dantoinal klinos
Dantoine
DB00252
Denyl
Di-Hydan
Di-Lan
Di-Lan (VAN)
Di-Phetine
Didan TDC 250
Didan-tdc-250
Difenilhidantoina
Difenilhidantoina [Spanish]
Difenin
Difetoin
Difhydan
Dihycon
Dihydan
Dihydan toin
Dihydantoin
Dilabid
Dilantin
Dilantin (TN)
Dilantin acid
Dilantin-125
DILANTIN-30
Dilantine
Dillantin
Dintoin
Dintoina
Diphantoin
Diphedal
Diphedan
Diphenat
Diphenat;
Diphenin
Diphenine
diphentoin
Diphentyn
Diphenylan
Diphenylan Sodium
Diphenylhydantoin
Diphenylhydantoin (VAN)
Diphenylhydantoine
Diphenylhydantoine [French]
Diphenylhydatanoin
Ditoinate
DivK1c_000507
DPH
DPH (VAN)
EINECS 200-328-6
Ekko
Ekko capsules
elepsi ndon
Elepsindon
Enkelfel
Epamin
epanutin
Epasmir "5"
epasmir ''5''
Epasmir 5
Epdantoin Simple
Epdantoine simple
Epelin
Epifenyl
Epihydan
Epilan
Epilan D
Epilan-D
Epilantin
Epinat
Epised
Eptal
eptoin
EU-0100378
EXTENDED PHENYTOIN SODIUM
fen toin
Fenantoin
Fenantoin Mn Pharma
Fenidantoin "s"
fenidantoin ''s''
Fenidantoin s
Fenitoin
Fenitoina
Fenitoina [INN-Spanish]
Fentoin
Fenylepsin
Fenytoin Dak
Fenytoine
Gerot-epilan-D
Hidan
Hidantal
Hidantilo
Hidantina
Hidantina senosian
Hidantina vitoria
Hidantomin
Hindatal
Hydantal
Hydantin
Hydantoin
Hydantoin, 5,5-diphenyl-
Hydantoin, 5,5-diphenyl- (8CI)
Hydantoinal
Hydantol
ictalis simp le
Ictalis simple
Idantoil
Idantoin
IDI1_000507
IDI1_008433
IFLab1_000214
Iphenylhydantoin
KBio1_000507
KBio2_001585
KBio2_004153
KBio2_006721
KBio3_001780
KBioGR_001387
KBioSS_001585
Kessodanten
Labopal
Lehydan
Lepitoin
Lepsin
Lopac-D-4007
Lopac0_000329
Lopac0_000378
LS-34
Mebroin
Minetoin
Mixture Name
MLS000069789
MLS001074087
NCGC00015342-01
NCGC00021139-01
NCGC00091492-01
NCGC00091492-02
NCGC00091492-03
NCGC00091492-04
NCGC00091492-05
NCGC00093810-01
NCGC00093810-02
NCI-C55765
Neos-Hidantoina
Neosidantoina
NINDS_000507
Novantoina
Novophenytoin
NSC 8722
NSC8722
Om hidantoina simple
Om-Hydantoine
Oprea1_373280
Oxylan
Phanantin
Phanatine
phenat ine
Phenatine
Phenatoine
phenhydan
Phenhydanin
phenitoin
Phentoin
PHENTYTOIN
PHENYTEK
PHENYTEX
Phenytoin
PHENYTOIN (5,5-DIPHENYLHYDANTOIN)
Phenytoin (JP15/USP/INN)
phenytoin (PHN)
Phenytoin AWD
Phenytoin Sodium
PHENYTOIN SODIUM, EXTENDED
Phenytoin [USAN:BAN:INN:JAN]
Phenytoin [USAN:INN:BAN:JAN]
Phenytoin, Lepitoin, Di-Hydan
Phenytoin-Gerot
Phenytoine
Phenytoine [INN-French]
Phenytoinum
Phenytoinum [INN-Latin]
PHT
Ritmenal
Saceril
Sanepil
Silantin
Sinergina
SMR000059026
Sodanthon
Sodantoin
Sodanton
Sodium Diphenylhydantoinate
Solantin
solantoin
solantyl
SPBio_001281
Spectrum2_001281
Spectrum3_000890
Spectrum4_000984
Spectrum5_001369
Spectrum_001105
ST5220927
STK058029
STK182871
Sylantoic
taco sal
tacosal
Thilophenyl
TOIN
Toin unicelles
WLN: T5MVMV EHJ ER& ER
Zentronal
Zentropil
ZINC02510358
ZINC18140189
ATC-Codes:
Side-Effects:
Side-EffectFrequency
constipation0
asthma0
palpitations0
hyperkalemia0
pancytopenia0
dysphagia0
ecchymosis0
thrombophlebitis0
anorexia0
migraine0
rhinitis0
polyuria0
vaginitis0
polyneuropathy0
somnolence0
infection0
polyarteritis nodosa0
dysarthria0
hemoptysis0
pelvic pain0
aphasia0
agitation0
dyskinesia0
deafness0
cardiomegaly0
heart failure0
nervousness0
eye pain0
subdural hematoma0
epilepsy0
lymphoma0
agranulocytosis0
encephalitis0
influenza0
tachycardia0
dermatitis0
dyspepsia0
chills0
amnesia0
toxic epidermal necrolysis0
insomnia0
sepsis0
cryptococcosis0
vomiting0
eosinophilia0
psychosis0
petechiae0
macrocytosis0
myalgia0
arthralgia0
hypotension0
leg cramps0
dysuria0
headache0
stupor0
thinking abnormal0
depersonalization0
albuminuria0
postural hypotension0
acidosis0
hypertrichosis0
vaginal moniliasis0
epistaxis0
thrombocytopenia0
leukocytosis0
hemorrhage0
gastritis0
flatulence0
lupus0
dehydration0
sweating0
renal failure0
cerebral infarction0
cerebral hemorrhage0
hypoxia0
dyspnea0
emotional lability0
lymphadenopathy0
hemiplegia0
paresthesia0
bronchitis0
nodule0
urinary retention0
visual field defect0
pain0
nausea0
syncope0
delirium0
photosensitivity0
meningitis0
bradycardia0
bundle branch block0
atrial flutter0
hypophosphatemia0
hypokalemia0
cachexia0
photophobia0
back pain0
ear pain0
diplopia0
ventricular extrasystoles0
hyperacusis0
increased salivation0
fever0
apnea0
contact dermatitis0
confusion0
stevens - johnson syndrome0
urinary incontinence0
hypertension0
pruritus0
urticaria0
dry mouth0
anemia0
cardiac arrest0
leukopenia0
atelectasis0
tinnitus0
pulmonary embolism0
encephalopathy0
gastrointestinal hemorrhage0
diabetes insipidus0
paralysis0
myopathy0
pneumothorax0
tremor0
hepatitis0
coma0
neurosis0
tenesmus0
hypochromic anemia0
shock0
megaloblastic anemia0
malaise0
nystagmus0
diarrhea0
alkalosis0
conjunctivitis0
pneumonia0
sinusitis0
sinus bradycardia0
cough0
amblyopia0
hypersensitivity0
pharyngitis0
hyperesthesia0
hyperglycemia0
edema0
dizziness0
ataxia0
ventricular fibrillation0
asthenia0
vertigo0
rash0

Target

show target details
Uniprot ID:CP2C9_HUMAN
Synonyms:
(R)-limonene 6-monooxygenase
(S)-limonene 6-monooxygenase
(S)-limonene 7-monooxygenase
CYPIIC9
Cytochrome P450 2C9
P-450MP
P450 MP-4/MP-8
P450 PB-1
S-mephenytoin 4-hydroxylase
EC-Numbers:1.14.13.48
1.14.13.49
1.14.13.80
Organism:Homo sapiens
Human
PDB IDs:1OG2 1OG5 1R9O
Structure:
1R9O

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
----
----
----
----
----
----
----
----
----
----
----
----
6000---
10000---

References: