Home
Drugs
Targets
Pathways
Ontologies
Cyp450s
Adv.search
Help/FAQ

Drug-Target Interaction

Drug

show drug details
PubChem ID:1649
Structure:
Synonyms:
1W-0945
3-Bromo-7-nitro-1H-indazole
3-bromo-7-nitro-2H-indazole
3-BROMO-7-NITROINDAZOLE
AC1L1BXC
AKOS005070136
B 2050
B2050_SIGMA
BCBcMAP01_000129
Bio1_000424
Bio1_000913
Bio1_001402
Bio2_000222
Bio2_000702
BRD-K24689407-001-03-0
BRD-K24689407-001-04-8
BSPBio_001502
BSPBio_002434
CCG-204256
CHEBI:47492
CHEBI:607592
CHEMBL479014
DB01997
EU-0100161
HMS1361L04
HMS1791L04
HMS1989L04
HMS3260B03
HSCI1_000239
IDI1_033972
INE
KBio2_000222
KBio2_002790
KBio2_005358
KBio3_000443
KBio3_000444
KBioGR_000222
KBioSS_000222
Lopac-B-2050
Lopac0_000161
MolPort-001-684-155
NCGC00015143-01
NCGC00015143-02
NCGC00015143-03
NCGC00015143-04
NCGC00015143-05
NCGC00015143-06
NCGC00015143-07
NCGC00015143-08
NCGC00015143-09
NCGC00015143-10
NCGC00024756-01
NCGC00024756-02
NCGC00024756-03
NCGC00024756-04
NCGC00024756-05
NCGC00024756-06
NCGC00024756-07
NCGC00024756-08
SPECTRUM1505105
ST50306995
ST5306995
Tocris-0735
ZINC03870920

Target

show target details
Uniprot ID:NOS2_MOUSE
Synonyms:
Inducible NO synthase
Inducible NOS
iNOS
MAC-NOS
Macrophage NOS
Nitric oxide synthase, inducible
NOS type II
EC-Numbers:1.14.13.39
Organism:Mouse
Mus musculus
PDB IDs:1DD7 1DF1 1DWV 1DWW 1DWX 1JWJ 1JWK 1M8D 1M8E 1M8H 1M8I 1M9T 1N2N 1NOC 1NOD 1NOS 1QOM 1QW4 1QW5 1R35 1VAF 2BHJ 2NOD 2NOS 2ORO 2ORP 2ORQ 2ORR 2ORS 2ORT 3DWJ 3E65 3E67 3E68 3E6L 3E6N 3E6O 3E6T 3E7I 3E7M 3E7T 3EAI 3EBD 3EBF 3NOD
Structure:
3NOD

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
----
--2200-

References: