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Drug-Target Interaction

Drug

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PubChem ID:16231
Structure:
Synonyms:
17440-83-4
1f5l
2016-88-8
2016-88-8 (HYDROCHLORIDE);17440-83-4 (HYDROCHLORIDE DIHYDRATE)
2609-46-3
3,5-diamino-6-chloro-N-(diaminomethylidene)pyrazine-2-carboxamide
3,5-Diamino-N-(aminoiminomethyl)-6-chloropyrazinecarboxamide
3,5-diamino-N-carbamimidoyl-6-chloropyrazine-2-carboxamide
3,5-diamino-N-[amino(imino)methyl]-6-chloropyrazine-2-carboxamide
AB00053415
AIDS-057138
AIDS057138
Amiclaran
Amiclaran (TN)
Amikal (Hydrochloride dihydrate)
Amilorida
Amilorida [INN-Spanish]
Amiloride
Amiloride (INN)
AMILORIDE (SEE ALSO: AMILORIDE HCL (2016-88-8))
Amiloride HCL
Amiloride hydrochloride
Amiloride hydrochloride hydrate
Amiloride [INN:BAN]
Amiloridum
Amiloridum [INN-Latin]
Amipramidin
Amipramizid
Amipramizide
Amiprazidine
AMR
Amyloride
BCBcMAP01_000101
Bio1_000359
Bio1_000848
Bio1_001337
Bio2_000292
Bio2_000772
BPBio1_000015
BSPBio_000013
BSPBio_001572
BSPBio_001826
C06821
C6H8ClN7O
CCRIS 6545
CHEBI:2639
CPD-10324
D07447
DB00594
DivK1c_000182
EINECS 220-024-7
Guanamprazin
Guanamprazine
IDI1_000182
IDI1_034042
KBio1_000182
KBio2_000292
KBio2_000394
KBio2_002860
KBio2_002962
KBio2_005428
KBio2_005530
KBio3_000583
KBio3_000584
KBio3_001326
KBioGR_000292
KBioGR_000544
KBioSS_000292
KBioSS_000394
Lopac-A-7410
Lopac0_000111
LS-1094
Midamor
Midamor (Hydrochloride dihydrate)
MK-870 (Hydrochloride dihydrate)
MLS000758249
MLS001060798
N-Amidino-3,5-diamino-6-chloropyrazinecarboxamide
N-Amidino-3,5-diamino-6-chlorpyrazincarboxamid
NCGC00015089-01
NCGC00015089-02
NCGC00024443-02
NCGC00024443-05
NCGC00024443-06
NCGC00024443-07
NCGC00024443-09
NINDS_000182
Prestwick0_000007
Prestwick1_000007
Prestwick2_000007
Prestwick3_000007
Pyrazinecarboxamide, 3,5-diamino-N-(aminoiminomethyl)-6-chloro-
Pyrazinecarboxamide, 3,5-diamino-N-(aminoiminomethyl)-6-chloro-,
Pyrazinecarboxamide, 3,5-diamino-N-(aminoiminomethyl)-6-chloro-, monohydrochloride
SMR000449325
SMR000486264
SPBio_000136
SPBio_001934
Spectrum2_000118
Spectrum3_000293
Spectrum4_000132
Spectrum5_000776
Spectrum_000034
ST079279
Tocris-0890
ZINC04340269
ATC-Codes:
Side-Effects:
Side-EffectFrequency
neutropenia0.0010
confusion0.0010
tremors0.0010
jaundice0.0010
liver disease0.0010
aplastic anemia0.0010
peptic ulcer0.0010
hepatic encephalopathy0.0010
coma0.0010
pruritus0
pulmonary edema0
purpura0
renal failure0
shock0
sialadenitis0
spasm0
polyuria0
pneumonia0
numbness0
nocturia0
pain0
palpitations0
bradycardia0
pancreatitis0
weakness0
paresthesia0
heartburn0
stevens - johnson syndrome0
syncope0
complete heart block0
muscle weakness0
malaise0
blurred vision0
shortness of breath0
paralysis0
urinary frequency0
increased sweating0
hyperuricemia0
agitation0
stupor0
encephalopathy0
tachycardia0
thrombocytopenia0
tinnitus0
urinary incontinence0
urticaria0
vasculitis0
vertigo0
vomiting0
dry mouth0
insomnia0
nervousness0
abdominal pain0
dehydration0
exfoliative dermatitis0
diarrhea0
dizziness0
somnolence0
dyspepsia0
dyspnea0
dysuria0
toxic epidermal necrolysis0
decreased libido0
cough0
alopecia0
anaphylaxis0
hemolytic anemia0
angina pectoris0
anorexia0
arthralgia0
back pain0
chest pain0
constipation0
erythema multiforme0
rash0
hyperglycemia0
hypersensitivity0
hyponatremia0
postural hypotension0
impotence0
leukopenia0
muscle cramps0
nasal congestion0
nausea0
hiccup0
heart block0
fatigue0
fever0
flatulence0
flushing0
gastrointestinal hemorrhage0
glycosuria0
gout0
gynecomastia0
headache0
interstitial nephritis0

Target

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Uniprot ID:CP1A1_HUMAN
Synonyms:
CYPIA1
Cytochrome P450 1A1
P450 form 6
P450-C
P450-P1
EC-Numbers:1.14.14.1
Organism:Homo sapiens
Human
PDB IDs:-

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
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References: