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Drug-Target Interaction

Drug

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PubChem ID:16038120
Structure:
Synonyms:
AKOS005145672
CHEBI:547450
CHEMBL509032
EC-000.2345
GUI
Kinome_1205
NVP-TAE684
S1108_Selleck
TAE684, NVP-TAE684

Target

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Uniprot ID:JAK2_HUMAN
Synonyms:
JAK-2
Janus kinase 2
Tyrosine-protein kinase JAK2
EC-Numbers:2.7.10.2
Organism:Homo sapiens
Human
PDB IDs:2B7A 2W1I 3E62 3E63 3E64 3FUP
Structure:
3FUP

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
--1505-

References: