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Drug-Target Interaction

Drug

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PubChem ID:16038120
Structure:
Synonyms:
AKOS005145672
CHEBI:547450
CHEMBL509032
EC-000.2345
GUI
Kinome_1205
NVP-TAE684
S1108_Selleck
TAE684, NVP-TAE684

Target

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Uniprot ID:INSR_HUMAN
Synonyms:
CD220
Insulin receptor
IR
EC-Numbers:2.7.10.1
Organism:Homo sapiens
Human
PDB IDs:1GAG 1I44 1IR3 1IRK 1P14 1RQQ 2AUH 2B4S 2DTG 2HR7 2Z8C 3BU3 3BU5 3BU6 3EKK 3EKN 3ETA
Structure:
3ETA

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
--20-
--10000-
---1000

References: