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Drug-Target Interaction

Drug

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PubChem ID:16038120
Structure:
Synonyms:
AKOS005145672
CHEBI:547450
CHEMBL509032
EC-000.2345
GUI
Kinome_1205
NVP-TAE684
S1108_Selleck
TAE684, NVP-TAE684

Target

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Uniprot ID:FGFR1_HUMAN
Synonyms:
Basic fibroblast growth factor receptor 1
bFGF-R
c-fgr
CD331
FGFR-1
Fms-like tyrosine kinase 2
EC-Numbers:2.7.10.1
Organism:Homo sapiens
Human
PDB IDs:1AGW 1CVS 1EVT 1FGI 1FGK 1FQ9 1XR0 2CR3 2FGI 3C4F 3GQI 3GQL
Structure:
3GQL

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
--1216-
--->1000

References: