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Drug-Target Interaction

Drug

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PubChem ID:158961
Structure:
Synonyms:
1H-Purine-2,6-dione, 3,7-dihydro-7-(2-hydroxypropyl)-1,3-dimethyl-, (S)-
7-[(2S)-2-hydroxypropyl]-1,3-dimethylpurine-2,6-dione
86540-95-6
AC1L4KXY
CAS-603-00-9
CHEBI:153813
CHEMBL290644
NCGC00016521-01
NCGC00018121-01
NCGC00018121-04
ZINC00057347

Target

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Uniprot ID:PDE5A_HUMAN
Synonyms:
CGB-PDE
cGMP-binding cGMP-specific phosphodiesterase
cGMP-specific 3',5'-cyclic phosphodiesterase
EC-Numbers:3.1.4.35
Organism:Homo sapiens
Human
PDB IDs:1RKP 1T9R 1T9S 1TBF 1UDT 1UDU 1UHO 1XOZ 1XP0 2CHM 2H40 2H42 2H44 3B2R 3BJC 3HC8 3HDZ
Structure:
3HDZ

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
600000---

References: