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Drug-Target Interaction

Drug

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PubChem ID:158
Structure:
Synonyms:
(-)-Prostaglandin E2
(15S)-Prostaglandin E2
(5Z,11.alpha.,13E,15S)-11,15-Dihydroxy-9-oxoprosta-5,13-dien-1-oic acid
(E,Z)-(1R,2R,3R)-7-[3-hydroxy-2-[(3S)-(3-hydroxy-1-octenyl)]-5-oxocyclopentyl]-5-heptenoic acid
363-24-6
5-Heptenoic acid, 7-[3-hydroxy-2-(3-hydroxy-1-octenyl)-5-oxocyclopentyl]-
7-[3-Hydroxy-2-(3-hydroxy-1-octenyl)-5-oxocyclopentyl]-5-heptenoic acid
Dinoprostone
NSC165560
NSC196514
PGE2
Prosta-5,13-dien-1-oic acid, (5Z,11.alpha.,13E,15S)-11,15-dihydroxy-9-oxo-
Prosta-5,13-dien-1-oic acid, 11,15-dihydroxy-9-oxo-,
Prosta-5,13-dien-1-oic acid, 11,15-dihydroxy-9-oxo-, (5Z,11.alpha.,13E,15S)-
Prosta-5,13-dien-1-oic acid, 11,5-dihydroxy-9-oxo-, (5Z,11.alpha.,13E,15S)-
Prostaglandin E(2)
Prostaglandin E2
Prostaglandin E2.alpha.
Prostarmon E
Prostin E2
U 12062
U,12,062
U-12062
Side-Effects:
Side-EffectFrequency
abdominal pain0.0010
diarrhea0.0010
fever0.0010
nausea0.0010
vomiting0.0010
nocturnal leg cramps0
urinary retention0
hearing loss0
sepsis0
chest pain0
hiccup0
neck rigidity0
tachycardia0
arrhythmia0
pain0
syncope0
tremor0
headache0
flushing0
hypotension0
hot flashes0
arthritis0
vaginitis0
myalgia0
arthralgia0
muscle cramps0
endometritis0
pharyngitis0
dyspnea0
myocardial infarction0
chills0
blurred vision0
breast tenderness0
acidosis0
bronchospasm0
paresthesia0
weakness0
back pain0
cough0
laryngitis0
eye pain0
dizziness0
dehydration0
wheezing0
increased sweating0
hypertension0
vulvitis0
hemorrhage0
bradycardia0
rash0

Target

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Uniprot ID:PE2R1_HUMAN
Synonyms:
PGE receptor, EP1 subtype
Prostaglandin E2 receptor EP1 subtype
Prostanoid EP1 receptor
EC-Numbers:-
Organism:Homo sapiens
Human
PDB IDs:-

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
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References: