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Drug-Target Interaction

Drug

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PubChem ID:156414
Structure:
Synonyms:
267243-28-7
Canertinib
Canertinib [INN]
Canertinib, PD-183805, CI1033, PD183805
CHEBI:61399
CI-1033
N-(4-((3-Chloro-4-fluorophenyl)amino)-7-(3-(morpholin-4-yl)propoxy)quinazo
N-(4-((3-Chloro-4-fluorophenyl)amino)-7-(3-(morpholin-4-yl)propoxy)quinazolin-6-yl)prop-2-enamide

Target

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Uniprot ID:MK10_HUMAN
Synonyms:
c-Jun N-terminal kinase 3
MAP kinase p49 3F12
Mitogen-activated protein kinase 10
Stress-activated protein kinase JNK3
EC-Numbers:2.7.11.24
Organism:Homo sapiens
Human
PDB IDs:1JNK 1PMN 1PMQ 1PMU 1PMV 2B1P 2EXC 2O0U 2O2U 2OK1 2P33 2R9S 2WAJ 2ZDT 2ZDU 3CGF 3CGO 3DA6 3FI2 3FI3 3FV8 3G90 3G9L 3G9N
Structure:
3G9N

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
-2800--
-5500--

References: