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Drug-Target Interaction

Drug

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PubChem ID:156414
Structure:
Synonyms:
267243-28-7
Canertinib
Canertinib [INN]
Canertinib, PD-183805, CI1033, PD183805
CHEBI:61399
CI-1033
N-(4-((3-Chloro-4-fluorophenyl)amino)-7-(3-(morpholin-4-yl)propoxy)quinazo
N-(4-((3-Chloro-4-fluorophenyl)amino)-7-(3-(morpholin-4-yl)propoxy)quinazolin-6-yl)prop-2-enamide

Target

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Uniprot ID:MAPK2_HUMAN
Synonyms:
MAP kinase-activated protein kinase 2
MAPK-activated protein kinase 2
MAPKAP kinase 2
MAPKAPK-2
MK2
EC-Numbers:2.7.11.1
Organism:Homo sapiens
Human
PDB IDs:1KWP 1NXK 1NY3 2JBO 2JBP 2OKR 2ONL 2OZA 2P3G 2PZY 3FPM 3FYJ 3FYK
Structure:
3FYK

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
->10000--

References: