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Drug-Target Interaction

Drug

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PubChem ID:151194
Structure:
Synonyms:
1-(4-chloroanilino)-4-(4-pyridylmethyl)phthalazine succinate
1-Phtalazinamine, N-(4-chlorophenyl)-4-(4-pyridinylmethyl)-
1-Phthalazinamine, N-(4-chlorophenyl)-4-(4-pyridinylmethyl)-
212141-54-3
AB1004881
AC1L45UC
CGP 79787
CGP-797870
CHEMBL101253
D06285
F9995-0196
HMS2089D11
I06-1922
K-222584
Kinome_3657
LS-187006
LS-187641
N-(4-Chlorophenyl)-4-(4-pyridinylmethyl)-1-phthalazinamine
N-(4-chlorophenyl)-4-(pyridin-4-ylmethyl)phtalazin-1-amine
N-(4-chlorophenyl)-4-(pyridin-4-ylmethyl)phthalazin-1-amine
NCGC00181350-01
NCGC00181350-02
nchembio778-comp1
PTK 787
PTK-787
PTK/ZK
Pynasunate
UNII-5DX9U76296
Vatalanib
Vatalanib (USAN/INN)
Vatalanib [USAN]
ZINC00007460
ZK-232934

Target

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Uniprot ID:MAPK2_HUMAN
Synonyms:
MAP kinase-activated protein kinase 2
MAPK-activated protein kinase 2
MAPKAP kinase 2
MAPKAPK-2
MK2
EC-Numbers:2.7.11.1
Organism:Homo sapiens
Human
PDB IDs:1KWP 1NXK 1NY3 2JBO 2JBP 2OKR 2ONL 2OZA 2P3G 2PZY 3FPM 3FYJ 3FYK
Structure:
3FYK

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
->10000--

References: