Home
Drugs
Targets
Pathways
Ontologies
Cyp450s
Adv.search
Help/FAQ

Drug-Target Interaction

Drug

show drug details
PubChem ID:151170
Structure:
Synonyms:
153259-65-5
1xlx
1xom
4-cyano-4-[3-(cyclopentyloxy)-4-methoxyphenyl]cyclohexane-1-carboxylic acid
Ariflo
Ariflo (TN)
Ariflo, SB-207499,Cilomilast
Cilomilast
Cilomilast (JAN/USAN/INN)
Cilomilast [USAN:INN]
CIO
cis-4-(3-(Cyclopentyloxy)-4-methoxyphenyl)-4-cyanocyclohexane-1-carboxylic
cis-4-(3-(Cyclopentyloxy)-4-methoxyphenyl)-4-cyanocyclohexane-1-carboxylic acid
cis-4-Cyano-4-(3-(cyclopentyloxy)-4-methoxyphenyl)cyclohexanecarboxylic acid
cis-4-Cyano-4-(3-cyclopentyloxy-4-methoxyphenyl)cyclohexanecarboxylic acid
CIS-4-CYANO-4-[3-(CYCLOPENTYLOXY)-4-METHOXYPHENYL]CYCLOHEXANECARBOXYLIC ACID
Cyclohexanecarboxylic acid, 4-cyano-4-(3-(cyclopentyloxy)-4-methoxyphenyl)-, cis-
D01704
DB03849
LS-56637
NCGC00167520-01
PDSP1_001287
PDSP2_001271
SB 207499
SB-207499
SB207499

Target

show target details
Uniprot ID:PDE4D_HUMAN
Synonyms:
cAMP-specific 3',5'-cyclic phosphodiesterase 4D
DPDE3
PDE43
EC-Numbers:3.1.4.17
Organism:Homo sapiens
Human
PDB IDs:1E9K 1MKD 1OYN 1PTW 1Q9M 1TB7 1TBB 1XOM 1XON 1XOQ 1XOR 1Y2B 1Y2C 1Y2D 1Y2E 1Y2K 1ZKN 2FM0 2FM5 2PW3 2QYN 3IAK
Structure:
3IAK

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
--39-
--63-
--79-

References: