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Drug-Target Interaction

Drug

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PubChem ID:149096
Structure:
Synonyms:
"(−)-ofloxacin"
(−)-Ofloxacin
(-)-(S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid
(-)-(S)-9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyridol[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid hemihydrate
(-)-(S)-9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7Hpyrido[1,2,3-de]-1,4 benzoxazine-6-carboxylic acid hemihydrate
(-)-(S)-9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7Hpyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid hemihydrate
(-)-Ofloxacin
(3S)-9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid
(R)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyr
(R)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid
(R)-isomer
(S)-(-)-Ofloxacin
(S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid
(S)-Ofloxacin
100986-85-4
100986-86-5
138199-71-0 (HEMIHYDRATE)
28266_FLUKA
28266_SIGMA
7H-Pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid, 2,3-dihydro-9-fluoro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-, (S)-
7H-Pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid, 9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-, (3S)-
AIDS-002307
AIDS002307
Ambap1065
BSPBio_002689
C07660
C18H20FN3O4
C18H20FN3O4.H2O
CCRIS 4073
CCRIS 4074
CPD000466387
Cravit
d-Levofloxacin
DB01137
DR 3354
DR-3355
DR-3355: L-isomer of ofloxacin
DR3355
DRG-0129
Elequine
Floxacin
HR 355
HR-355
Iquix
KBio2_002199
KBio2_004767
KBio2_007335
KBio3_001909
KBioGR_001605
KBioSS_002199
KS-1077
L-Ofloxacin
Levaquin
LEVAQUIN IN DEXTROSE 5% IN PLASTIC CONTAINER
Levofloxacin
Levofloxacin tablet, suspension or intravenous
Levofloxacin [USAN:INN:JAN]
Levofloxacine
Levofloxacine [INN-French]
Levofloxacino
Levofloxacino [INN-Spanish]
Levofloxacinum
Levofloxacinum [INN-Latin]
LS-133260
LS-171761
LVX
MLS000759524
MLS001165709
MLS001423977
MP-376
NCGC00178529-01
Ofloxacin S-(-)-form
Oftaquix
QUIXIN
R-Ofloxacin
RWJ 25213-097
RWJ-25213
S-(-)-Ofloxacin
SAM001246758
SMR000466387
SPBio_001891
SPECTRUM1504260
Spectrum2_001676
Spectrum3_000995
Spectrum4_001123
Spectrum5_001438
Spectrum_001719
Tavanic
ATC-Codes:

Target

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Uniprot ID:GYRB_ECOLI
Synonyms:
DNA gyrase subunit B
EC-Numbers:5.99.1.3
Organism:Escherichia coli
strain K12
PDB IDs:1AJ6 1EI1 1KZN
Structure:
1KZN

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
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References: