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Drug-Target Interaction

Drug

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PubChem ID:14888
Structure:
Synonyms:
1327-53-3
28380-38-3
AC1L24QX
Acide arsenieux [French]
AI3-01163
Anhydride arsenieux [French]
Arseni trioxydum
Arsenic (III) oxide
Arsenic blanc [French]
Arsenic oxide
Arsenic oxide (As2O3)
Arsenic sesquioxide
ARSENIC TRIOXIDE
Arsenic trioxide (JP15/USAN)
Arsenic trioxide (JP16/USAN)
Arsenic trioxide [JAN]
Arsenic trioxide [UN1561] [Poison]
Arsenic trioxide [UN1561] [Poison]
arsenic(3+)
Arsenic(III) oxide
Arsenic(III) trioxide
Arsenicum album
Arsenigen saure [German]
Arsenious acid
Arsenious Acid Anhydride
Arsenious oxide
Arsenious trioxide
Arsenite
Arsenolite
Arsenous acid
Arsenous acid anhydride
Arsenous anhydride
Arsenous oxide
Arsenous oxide anhydride
Arsenous oxide [ISO]
Arsenox
Arsentrioxide
Arsodent
C006632
C13619
Caswell No. 059
CCRIS 5455
CHEMBL405991
Claudelite
Claudetite
Crude arsenic
D02106
Diarsenic trioxide
EINECS 215-481-4
EPA Pesticide Chemical Code 007001
HSDB 419
LS-761
Oxyde Arsenieux
Oxyde Arsenieux [ISO-French]
oxygen(2-)
RCRA waste no. P012
RCRA waste number P012
tricyclo[3.3.1.1~3,7~]tetraarsoxane
Trisenox
Trisenox (TN)
Trixenox
UN 1561
UN1561
UNII-S7V92P67HO
White arsenic
Side-Effects:
Side-EffectFrequency
neck pain0
dyspepsia0
petechiae0
tremor0
palpitations0
hyperkalemia0
ecchymosis0
anorexia0
somnolence0
infection0
blistering0
dermatitis0
tachycardia0
heart disease0
bacterial infections0
weight loss0
nasopharyngitis0
rash0
constipation0
weakness0
paresthesia0
dry skin0
vascular disorders0
sgot increased0
acidosis0
cough0
sepsis0
vomiting0
blood dyscrasia0
dry eyes0
myalgia0
arthralgia0
upper respiratory tract infection0
eye redness0
increased sweating0
hypotension0
insomnia0
vaginal hemorrhage0
fecal incontinence0
epistaxis0
thrombocytopenia0
leukocytosis0
hemorrhage0
neutropenia0
wheezing0
abdominal distention0
abdominal pain0
weight gain0
dyspnea0
headache0
coma0
lymphadenopathy0
dry mouth0
anemia0
arrhythmia0
chest pain0
hypoxia0
pain0
pain in limb0
herpes simplex0
metrorrhagia0
nausea0
renal failure0
urticaria0
bone pain0
erythema0
agitation0
back pain0
ear pain0
fever0
drug hypersensitivity0
confusion0
urinary incontinence0
hypertension0
pruritus0
postnasal drip0
hypomagnesemia0
hypocalcemia0
fatigue0
vertigo0
diarrhea0
tinnitus0
oral moniliasis0
gastrointestinal hemorrhage0
herpes zoster0
hemoptysis0
anxiety0
dizziness0
hypoglycemia0
edema0
hypokalemia0
pleural effusion0
flushing0
ecg abnormal0
sinusitis0
hyperpigmentation0
blurred vision0
sore throat0
hyperglycemia0
night sweats0
seizures0

Target

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Uniprot ID:MK03_HUMAN
Synonyms:
ERK-1
ERT2
Extracellular signal-regulated kinase 1
Insulin-stimulated MAP2 kinase
MAP kinase 1
MAPK 1
Microtubule-associated protein 2 kinase
Mitogen-activated protein kinase 3
p44-ERK1
p44-MAPK
EC-Numbers:2.7.11.24
Organism:Homo sapiens
Human
PDB IDs:2ZOQ
Structure:
2ZOQ

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
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References: