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Drug-Target Interaction

Drug

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PubChem ID:1348
Structure:
Synonyms:
1-(3-Chlorophenylamino)-4-phenylphthalazine
1-Phthalazinamine, N-(3-chlorophenyl)-4-phenyl-
78351-75-4
AC1L1BA2
AC1Q3KA0
AC1Q3OYW
AR-1J8533
Bio2_000080
Bio2_000560
BRD-K90524085-001-05-2
BSPBio_001360
BSPBio_003225
C052490
CHEBI:296620
CHEMBL332898
DivK1c_006903
HMS1361D22
HMS1791D22
HMS1989D22
IDI1_033830
IN1232
KBio1_001847
KBio2_000080
KBio2_002648
KBio2_005216
KBio3_000159
KBio3_000160
KBio3_002725
KBioGR_000080
KBioSS_000080
MY 5445
MY-5445
n-(3-chlorophenyl)-4-phenylphthalazin-1-amine
NCGC00024587-01
NCGC00024587-02
NCGC00024587-03
NCGC00024587-04
NCGC00024587-05
SMP2_000185
SPBio_001839
SpecPlus_000807
Spectrum2_001820
Spectrum3_001763
Tocris-0432
ZINC02557949

Target

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Uniprot ID:PDE5A_HUMAN
Synonyms:
CGB-PDE
cGMP-binding cGMP-specific phosphodiesterase
cGMP-specific 3',5'-cyclic phosphodiesterase
EC-Numbers:3.1.4.35
Organism:Homo sapiens
Human
PDB IDs:1RKP 1T9R 1T9S 1TBF 1UDT 1UDU 1UHO 1XOZ 1XP0 2CHM 2H40 2H42 2H44 3B2R 3BJC 3HC8 3HDZ
Structure:
3HDZ

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
--5000-

References: