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Drug-Target Interaction

Drug

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PubChem ID:13009345
Structure:
Synonyms:
CHEBI:321701
CHEMBL135491

Target

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Uniprot ID:TOP1_HUMAN
Synonyms:
DNA topoisomerase 1
DNA topoisomerase I
EC-Numbers:5.99.1.2
Organism:Homo sapiens
Human
PDB IDs:1A31 1A35 1A36 1EJ9 1K4S 1K4T 1LPQ 1NH3 1R49 1RR8 1RRJ 1SC7 1SEU 1T8I 1TL8
Structure:
1TL8

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
---17

References: