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Drug-Target Interaction

Drug

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PubChem ID:127757
Structure:
Synonyms:
(S)-3-(8-((Dimethylamino)methyl)-6,7,8,9-tetrahydropyrido(1,2-a)indol-10-y
(S)-3-(8-((Dimethylamino)methyl)-6,7,8,9-tetrahydropyrido(1,2-a)indol-10-yl)-4-(1-methyl-1H-indol-3-yl)-1H-pyrrol-2,5-dione
(S)-3-(8-(Dimethylaminomethyl)-6,7,8,9-tetrahydropyrido(1,2-a)indol-10-yl)-4-(1-methyl-3-indolyl)-1H-pyrrole-2,5-dione hydrochloride
151342-35-7
1H-Pyrrol-2,5-dione, 3-(8-((dimethylamino)methyl)-6,7,8,9-tetrahydropyrido(1,2-a)indol-10-yl)-4-(1-methyl-1H-indol-3-yl)-, (S)-
1H-Pyrrole-2,5-dione, 3-(8-((dimethylamino)methyl)-6,7,8,9-tetrahydropyrido(1,2-a)indol-10-yl)-4-(1-methyl-1H-indol-3-yl)-, (S)-
C28H28N4O2.HCl
LS-173403
Ro 32-0432
Ro-32-0432

Target

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Uniprot ID:GSK3B_HUMAN
Synonyms:
Glycogen synthase kinase-3 beta
GSK-3 beta
EC-Numbers:2.7.11.26
Organism:Homo sapiens
Human
PDB IDs:1GNG 1H8F 1I09 1J1B 1J1C 1O9U 1PYX 1Q3D 1Q3W 1Q41 1Q4L 1Q5K 1R0E 1UV5 2JDO 2JDR 2JLD 2O5K 2OW3 2UW9 3CQU 3CQW 3DU8 3E87 3E88 3E8D 3F7Z 3F88
Structure:
3F88

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
--20-

References: