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Drug-Target Interaction

Drug

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PubChem ID:126569
Structure:
Synonyms:
(S)-(-)-5-fluorowillardine
(S)-alpha-Amino-5-fluoro-3,4-dihydro-2,4-dioxo-1(2H)-pyrimmidinepropanoic acid
1(2H)-Pyrimmidinepropanoic acid, alpha-amino-5-fluoro-3,4-dihydro-2,4-dioxo-, (S)-
140187-23-1
1mqi
2-AMINO-3-(5-FLUORO-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC
2-AMINO-3-(5-FLUORO-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID
3-(5-fluoro-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-L-alanine
5-Fluorowillardiine
FLUORO-WILLARDIINE
FWD
NCGC00024528-01
PDSP1_001836
PDSP2_001819
Tocris-0306

Target

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Uniprot ID:GRIK2_RAT
Synonyms:
GluR-6
GluR6
Glutamate receptor 6
Glutamate receptor, ionotropic kainate 2
EC-Numbers:-
Organism:Rat
Rattus norvegicus
PDB IDs:1S50 1S7Y 1S9T 1SD3 1TT1 1YAE 2I0B 2I0C 3G3F 3G3G 3G3H 3G3I 3G3J 3G3K 3H6G 3H6H
Structure:
3H6H

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
>100000---

References: