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Drug-Target Interaction

Drug

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PubChem ID:126569
Structure:
Synonyms:
(S)-(-)-5-fluorowillardine
(S)-alpha-Amino-5-fluoro-3,4-dihydro-2,4-dioxo-1(2H)-pyrimmidinepropanoic acid
1(2H)-Pyrimmidinepropanoic acid, alpha-amino-5-fluoro-3,4-dihydro-2,4-dioxo-, (S)-
140187-23-1
1mqi
2-AMINO-3-(5-FLUORO-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC
2-AMINO-3-(5-FLUORO-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID
3-(5-fluoro-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-L-alanine
5-Fluorowillardiine
FLUORO-WILLARDIINE
FWD
NCGC00024528-01
PDSP1_001836
PDSP2_001819
Tocris-0306

Target

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Uniprot ID:GRIA1_HUMAN
Synonyms:
AMPA-selective glutamate receptor 1
GluR-1
GluR-A
GluR-K1
Glutamate receptor 1
Glutamate receptor ionotropic, AMPA 1
EC-Numbers:-
Organism:Homo sapiens
Human
PDB IDs:-

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
14.7---
---380
---382

References: