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Drug-Target Interaction

Drug

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PubChem ID:123985
Structure:
Synonyms:
()-oxazepam hemisuccinate sodium salt
(2S,3S)-3-((S)-1-(4-Guanidinobutylamino)-4-methyl-1-oxopentan-2-ylcarbamoyl)oxirane-2-carboxylic acid
(2S,3S)-3-(N-{(S)-1-[N-(4-guanidinobutyl)carbamoyl]3-methylbutyl}carbamoyl)oxirane-2-carboxylic acid
(2s,3s)-3-({(2s)-1-[(4-carbamimidamidobutyl)amino]-4-methyl-1-oxopentan-2-
(2S,3S)-3-[((1S)-1-{[4-(carbamimidamido)butyl]carbamoyl}-3-methylbutyl)carbamoyl]oxirane-2-carboxylic acid
5-18-07-00006 (Beilstein Handbook Reference)
66701-25-5
BRN 1405664
C15H27N5O5
CHEBI:30270
E 64
E 64 (proteinase inhibitor)
E-64
E64
L-trans-epoxysuccinyl-leucylamido(4-guanidino)butane
LS-100998
N-(N-(L-3-trans-carboxyoxirane-2-carbonyl)-L-leucyl)agmatine
NCGC00163544-01
nchembio.104-comp2
Oxiranecarboxylic acid, 3-(((1-(((4-((aminoiminomethyl)amino)butyl)amino)carbonyl)-3-methylbutyl)amino)carbonyl)-, (2S-(2-alpha,3-beta(R*)))-
Proteinase inhibitor E 64
Thiol protease inhibitor

Target

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Uniprot ID:CATS_HUMAN
Synonyms:
Cathepsin S
EC-Numbers:3.4.22.27
Organism:Homo sapiens
Human
PDB IDs:1BXF 1GLO 1MS6 1NPZ 1NQC 2C0Y 2F1G 2FQ9 2FRA 2FRQ 2FT2 2FUD 2FYE 2G6D 2G7Y 2H7J 2HH5 2HHN 2HXZ 2OP3 2R9M 2R9N 2R9O
Structure:
2R9O

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
--7-

References: