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Drug-Target Interaction

Drug

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PubChem ID:122316
Structure:
Synonyms:
1875-50-9
1H-Inden-1-amine, 2,3-dihydro-N-2-propynyl-
2,3-Dihydro-N-2-propynyl-1H-inden-1-amine
AC1L3UDA
AC1Q286P
Agn 1135
Agn-1135
AKOS000223747
AR-1K5582
CHEMBL295093
CID122316
N-2-Propynyl-1-indanamine
N-prop-2-ynyl-2,3-dihydro-1H-inden-1-amine
rasagiline
Side-Effects:
Side-EffectFrequency
bundle branch block1.0
gastrointestinal hemorrhage1.0
neuropathy1.0
hematuria1.0
tremor1.0
cough1.0
urinary incontinence1.0
abnormal gait1.0
asthenia1.0
anxiety1.0
headache0.14
dyspepsia0.07
arthralgia0.07
flu syndrome0.05
rhinitis0.03
fever0.03
gastroenteritis0.03
conjunctivitis0.03
vertigo0.02
malaise0.02
ecchymosis0.02
arthritis0.02
neck pain0.02
paresthesia0.012499999
polyuria0.01
pleural effusion0.01
pneumothorax0.01
muscle atrophy0.01
phlebitis0.01
personality disorder0.01
myocardial infarct0.01
bone necrosis0.01
nocturia0.01
neurosis0.01
neuritis0.01
esophageal ulcer0.01
chills0.01
urinary retention0.01
ventricular tachycardia0.01
mouth ulceration0.01
vaginitis0.01
urticaria0.01
stomatitis0.01
stomach ulcer0.01
visual field defect0.01
vaginal hemorrhage0.01
retinal degeneration0.01
eye pain0.01
deep thrombophlebitis0.01
emphysema0.01
psychosis0.01
ptosis0.01
convulsion0.01
agitation0.01
aphasia0.01
esophagitis0.01
dysarthria0.01
eczema0.01
dysuria0.01
dysmenorrhea0.01
diplopia0.01
dementia0.01
deafness0.01
colitis0.01
vaginal moniliasis0.01
heart failure0.01
blepharitis0.01
macrocytic anemia0.01
apnea0.01
facial paralysis0.01
fecal incontinence0.01
flank pain0.01
kidney calculus0.01
migraine0.01
hypocalcemia0.01
keratitis0.01
acute kidney failure0.01
hemiplegia0.01
glaucoma0.01
photosensitivity0.01
dysesthesia0.01
hemorrhage0.01
edema0.0054999995
arthrosis0.0040
interstitial pneumonia0.0010
photophobia0.0010
cerebral ischemia0.0010
leukoderma0.0010
av block second degree0.0010
hemorrhagic gastritis0.0010
hydroureter0.0010
bigeminy0.0010
av block complete0.0010
blindness0.0010
thrombocythemia0.0010
vestibular disorder0.0010
intestinal perforation0.0010
hematemesis0.0010
amenorrhea0.0010
gynecomastia0.0010
epididymitis0.0010
exfoliative dermatitis0.0010
delirium0.0010
cerebral hemorrhage0.0010
manic depressive reaction0.0010
arrhythmia0.0010
jaundice0.0010
megacolon0.0010
ventricular fibrillation0.0010
strabismus0.0010
retinal hemorrhage0.0010
retinal detachment0.0010
purpura0.0010
lung fibrosis0.0010
priapism0.0010
neuralgia0.0010
myelitis0.0010
melena0.0010
amnesia0
epistaxis0
albuminuria0
sweating0
infection0
somnolence0
dysphagia0
asthma0
liver function tests abnormal0
hernia0
dyskinesia0
abdominal pain0
dyspnea0
apathy0
emotional lability0
manic0
stupor0
leg cramps0
hallucinations0
tenosynovitis0
vomiting0
angina pectoris0
postural hypotension0
delusions0
constipation0
anorexia0
alopecia0
syncope0
nausea0
decreased libido0
chest pain0
anemia0
dry mouth0
pruritus0
confusion0
skin carcinoma0
leukopenia0
rash0
weight loss0
allergic reaction0
diarrhea0
ataxia0
impotence0
skin ulcer0
gingivitis0
bursitis0
cerebrovascular accident0
dizziness0

Target

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Uniprot ID:CP1A2_HUMAN
Synonyms:
CYPIA2
Cytochrome P450 1A2
P(3)450
P450 4
P450-P3
EC-Numbers:1.14.14.1
Organism:Homo sapiens
Human
PDB IDs:2HI4
Structure:
2HI4

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
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References: