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Drug-Target Interaction

Drug

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PubChem ID:119031
Structure:
Synonyms:
(2R,3S)-N-[(2S)-3,3-dimethyl-1-methylamino-1-oxobutan-2-yl]-N',3-dihydroxy-2-(2-methylpropyl)butanediamide
(2S,3R)-3-(((1S)-2,2-Dimethyl-1-(methylcarbamoxy)propyl)carboyl)-2-hydroxy-5-methylhexanohydroxamic acid
(2S,3R)-3-(((1S)-2,2-Dimethyl-1-(methylcarbamoyl)propyl)carbamoyl)-2-hydroxy-5-methylhexanohydroxamic acid
(2S,3R)-N(4)-[(2S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl]-N(1),2-dihydroxy-3-(2-methylpropyl)butanediamide
154039-60-8
BB 2516
BB-2516
Butanediamide,
Butanediamide, N(sup 4)-(2,2-dimethyl-1-((methylamino)carbonyl)propyl)-N(sup 1),2-dihydroxy-3-(2-methylpropyl)-, (2S-(N(sup 4)(R*),2R*,3S*))-
Butanediamide, N4-((1S)-2,2-dimethyl-1-((methylamino)carbonyl)propyl)-N1,2-dihydroxy-3-(2-methylpropyl)-, (2S,3R)-
Butanediamide, N4-(2,2-dimethyl-1-((methylamino)carbonyl)propyl)-N1,2-dihydroxy-3-(2-methylpropyl)-, (2S-(N4(R*),2R*,3S*))-
C100342
C15H29N3O5
CHEBI:50662
D03795
DB00786
LS-45634
Marimastat
Marimastat (USAN/INN)
Marimastat [USAN]

Target

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Uniprot ID:MMP14_HUMAN
Synonyms:
Matrix metalloproteinase-14
Membrane-type matrix metalloproteinase 1
Membrane-type-1 matrix metalloproteinase
MMP-14
MMP-X1
MT-MMP 1
MT1-MMP
MT1MMP
MTMMP1
EC-Numbers:3.4.24.80
Organism:Homo sapiens
Human
PDB IDs:1BQQ 1BUV 3C7X
Structure:
3C7X

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
--1.82-

References: