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Drug-Target Interaction

Drug

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PubChem ID:1176
Structure:
Synonyms:
173144-80-4
173994-65-5
174693-33-5
175276-38-7
299367_ALDRICH
30535-50-3
33247_RIEDEL
33247_SIAL
37955-36-5
4744-36-9
506-89-8
51456_FLUKA
51456_SIGMA
51457_FLUKA
51457_SIGMA
51459_FLUKA
51459_SIAL
51460_FLUKA
51460_SIAL
51465_FLUKA
57-13-6
6E4EB293-4363-4D38-BF3B-1397372C31E5
860639-56-1
AB1002498
AC1L1AWB
AC1Q50ED
AG-G-01350
AI3-01202
AIDS-003652
AIDS003652
Alphadrate
Aqua Care
Aqua Care HP
Aquacare
Aquacare HP
Aquadrate
ARF
B-I-K
basodexan
Benural 70
bromisovalum
BSPBio_003341
C00086
c0165
Calmurid
Carbaderm
carbamide
Carbamide resin
Carbamide: Carbonyl diamide
Carbamimic acid
Carbamimidic acid
Carbamimidic acid (VAN)
carbonamidimidic acid
Carbonyl diamide
Carbonyldiamide
Carbonyldiamine
carmol
Carmol 40
Caswell No. 902
CCG-40265
CCRIS 989
Cerovel
CHEBI:16199
CHEBI:48376
CHEMBL985
component of Artra Ashy Skin Cream
D00023
D014508
DB03904
DivK1c_000086
EINECS 200-315-5
Elaqua XX
EPA Pesticide Chemical Code 085702
Eucerin 10% Urea Lotion
H2N-C(=NH)-OH
H2N-C(OH)=NH
H2NC(O)NH2
Harnstoff
Harnstoff [German]
HMS1921I17
HMS2092C08
HMS2232P21
HMS500E08
HO-C(=NH)-NH2
HSDB 163
Hyanit
I14-0449
IDI1_000086
Isoharnstoff
Isourea
Karbamid
KBio1_000086
KBio2_001152
KBio2_003720
KBio2_006288
KBio3_002843
KBioGR_001775
KBioSS_001152
Keratinamin
Keratinamin Kowa
LS-1389
LTBB002324
Mixture Name
MLS001076688
Mocovina
Mocovina [Czech]
NCGC00090892-01
NCGC00090892-02
NCGC00090892-03
NCGC00090892-04
NCGC00090892-05
NCGC00090892-06
nchembio.265-comp3
NCI-C02119
NINDS_000086
NSC 34375
NSC34375
Nutraplus
Onychomal
Optigen 1200
Panafil
Pastaron
Pastaron (TN)
Pastaron 10
Pastaron 20
Pastaron 20 soft
Pastaron soft
Polyurea
Prespersion, 75 urea
Pseudourea
Rubinol ST 010
SMR000499585
SPBio_001263
SPECTRUM1500604
Spectrum2_001192
Spectrum3_001791
Spectrum4_001168
Spectrum5_001862
Spectrum_000672
ST5214565
Supercel 3000
U0077
U0631_SIGMA
U1250_SIAL
U1250_SIGMA
U4128_SIGMA
U4883_SIGMA
U4884_SIGMA
U5128_SIAL
U5378_SIGMA
U6504_SIGMA
U7129_SIGMA
Ultra Mide
UNII-8W8T17847W
UR
URE
UREA
Urea (8CI,9CI)
Urea (JP15/USP)
Urea (JP16/USP)
Urea ammonium nitrate solution
Urea perhydrate
Urea solution
Urea [JAN]
UREA, ACS
Urea, homopolymer
UREA, U.S.P.
UREA, ULTRA PURE
Urea-12C
Urea-13C
Ureacin-10 lotion
Ureacin-20
Ureacin-40 Creme
Ureaphil
uree
Ureophil
Urepeal
Urepeal L
Urepearl
Ureum
Urevert
Varioform II
WLN: ZVZ
ZINC08214514
ATC-Codes:

Target

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Uniprot ID:A4TB13_MYCGI
Synonyms:
Amine oxidase (Copper-containing)
EC-Numbers:1.4.3.6
Organism:Mycobacterium flavescens (strain ATCC 700033 / PYR-GCK
Mycobacterium gilvum
strain PYR-GCK
PDB IDs:-

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
----

References:

1269
Time-dependent inhibition of diamine oxidase by carbonyl-group reagents and urea.. M J Crabbe; R E Childs; W G Bardsley (1975) European journal of biochemistry / FEBS display abstract
1. The behaviour of several carbonyl group reagents and urea as time-dependent inhibitors of both pig kidney and human placental diamine oxidase is described. 2. Plots of log (vt/vo) against time were not linear with these reagents as the usual theories predict. 3. This was particularly the case with aminoguanidine and phenylhydrazine and a thorough study of the effects of these compounds on the human placental diamine oxidase is described. 4. By applying a new theory for time-dependent inhibition, the inhibition of diamine oxidase by aminoguanidine and phenylhydrazine is adequately accounted for. 5. The time-dependent recovery of activity on addition of sodium pyruvate suggested that the compounds used are acting solely as carbonyl group reagents, inhibiting by Schiff-base formation at the active-site carbonyl group.