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Drug-Target Interaction

Drug

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PubChem ID:11667893
Structure:
Synonyms:
()-oxazepam hemisuccinate sodium salt
453562-69-1
AMG 706
AMG-706
CHEBI:51098
D06678
Motesanib
N-(2,3-dihydro-3,3-dimethyl-1H-indol-6-yl)-2-((4-pyridinylmethyl)amino)-3-pyridinecarboxamide
N-(3,3-dimethyl-2,3-dihydro-1H-indol-6-yl)-2-[(pyridin-4-ylmethyl)amino]py
N-(3,3-dimethyl-2,3-dihydro-1H-indol-6-yl)-2-[(pyridin-4-ylmethyl)amino]pyridine-3-carboxamide
ZINC18710082

Target

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Uniprot ID:RET_HUMAN
Synonyms:
C-ret
Proto-oncogene tyrosine-protein kinase receptor ret
EC-Numbers:2.7.10.1
Organism:Homo sapiens
Human
PDB IDs:1XPD 2IVS 2IVT 2IVU 2IVV
Structure:
2IVV

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
-14--
-20--
--59-

References: