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Drug-Target Interaction

Drug

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PubChem ID:11485656
Structure:
Synonyms:
()-oxazepam hemisuccinate sodium salt
796967-16-3
ABT 869
ABT-869
ABT869, Linifanib, AL-39324, RG3635
AL-39324
CHEMBL223360
D09635
EC-000.2119
Kinome_532
Linifanib
Linifanib (USAN/INN)
N-(4-(3-Amino-1H-indazol-4-yl)phenyl)-N'-(2-fluoro-5-methylphenyl)urea
N-(4-(3-Amino-1H-indazol-4-yl)phenyl)-N1-(2-fluoro-5-methylphenyl)urea
RG-3635
S06-0034
S1003_Selleck
Urea, N-(4-(3-amino-1H-indazol-4-yl)phenyl)-N'-(2-fluoro-5-methylphenyl)-

Target

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Uniprot ID:MK03_HUMAN
Synonyms:
ERK-1
ERT2
Extracellular signal-regulated kinase 1
Insulin-stimulated MAP2 kinase
MAP kinase 1
MAPK 1
Microtubule-associated protein 2 kinase
Mitogen-activated protein kinase 3
p44-ERK1
p44-MAPK
EC-Numbers:2.7.11.24
Organism:Homo sapiens
Human
PDB IDs:2ZOQ
Structure:
2ZOQ

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
->10000--

References: