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Drug-Target Interaction

Drug

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PubChem ID:11485656
Structure:
Synonyms:
()-oxazepam hemisuccinate sodium salt
796967-16-3
ABT 869
ABT-869
ABT869, Linifanib, AL-39324, RG3635
AL-39324
CHEMBL223360
D09635
EC-000.2119
Kinome_532
Linifanib
Linifanib (USAN/INN)
N-(4-(3-Amino-1H-indazol-4-yl)phenyl)-N'-(2-fluoro-5-methylphenyl)urea
N-(4-(3-Amino-1H-indazol-4-yl)phenyl)-N1-(2-fluoro-5-methylphenyl)urea
RG-3635
S06-0034
S1003_Selleck
Urea, N-(4-(3-amino-1H-indazol-4-yl)phenyl)-N'-(2-fluoro-5-methylphenyl)-

Target

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Uniprot ID:MAPK2_HUMAN
Synonyms:
MAP kinase-activated protein kinase 2
MAPK-activated protein kinase 2
MAPKAP kinase 2
MAPKAPK-2
MK2
EC-Numbers:2.7.11.1
Organism:Homo sapiens
Human
PDB IDs:1KWP 1NXK 1NY3 2JBO 2JBP 2OKR 2ONL 2OZA 2P3G 2PZY 3FPM 3FYJ 3FYK
Structure:
3FYK

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
->10000--

References: