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Drug-Target Interaction

Drug

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PubChem ID:1110
Structure:
Synonyms:
1,2-Ethanedicarboxylic acid
1,4-Butanedioic acid
1,4-BUTANEDIOIC ACID (SUCCINIC ACID)
1,4-BUTANEDIOIC ACID (SUCCINIC ACID)
110-15-6
14078_FLUKA
14079_FLUKA
14079_SIAL
1cze
37E8FFFB-70DA-4399-B724-476BD8715EF0
398055_SIAL
4-02-00-01908 (Beilstein Handbook Reference)
623158-99-6
6283-68-7
A 12084
AC1L1AQW
AC1Q757B
Acid of amber
acide butanedioique
acide succinique
Acidum succinicum
AG-D-27403
AI3-06297
AIDS-017693
AIDS017693
AKOS000118899
Amber acid
Amber acid, Butanedioic acid, Ethylenesuccinic acid
Ammonium succinate
Asuccin
BBL002473
Bernsteinsaeure
Bernsteinsaure
Bernsteinsaure [German]
bmse000183
BRN 1754069
Butandisaeure
Butanedioic acid
Butanedioic acid (9CI)
Butanedioic acid diammonium salt
Butanedionic acid
C00042
C4H6O4
CHEBI:15741
CHEMBL576
DB00139
Dicarboxylic acid
Dihydrofumaric acid
EINECS 203-740-4
Ethanedicarboxylic acid
Ethylene dicarboxylic acid
Ethylene succinic acid
Ethylenesuccinic acid
FMR
FUM
HOOC-CH2-CH2-COOH
HSDB 791
I04-1083
Katasuccin
Kyselina jantarova
Kyselina jantarova [Czech]
LMFA01170043
LS-147378
MAE
NCGC00159372-02
NCGC00159372-03
NCGC00159372-04
NCGC00159372-05
nchembio.186-comp50
nchembio.198-comp17
nchembio.2007.47-comp2
nchembio.266-comp26
nchembio856-comp9
NSC 106449
NSC106449
NSC25949
Potassium Succinate
S0100
S3674_SIAL
S7501_SIAL
S9512_SIGMA
Sal succini
SBB040562
SIN
spirit of amber
ST5213944
STK387105
suc
succ
Succinate
succinate, 9
Succinellite
Succinic acid
Succinic acid (8CI)
SUCCINIC ACID, ACS
Succinicum acidum
Succinicun acidum
UNII-AB6MNQ6J6L
W502707_ALDRICH
W502715_ALDRICH
WLN: QV2VQ
Wormwood
Wormwood acid

Target

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Uniprot ID:SSDH_HUMAN
Synonyms:
Aldehyde dehydrogenase family 5 member A1
NAD(+)-dependent succinic semialdehyde dehydrogenase
Succinate-semialdehyde dehydrogenase, mitochondrial
EC-Numbers:1.2.1.24
Organism:Homo sapiens
Human
PDB IDs:2W8N 2W8O 2W8P 2W8Q 2W8R
Structure:
2W8R

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
----

References: