Home
Drugs
Targets
Pathways
Ontologies
Cyp450s
Adv.search
Help/FAQ

Drug-Target Interaction

Drug

show drug details
PubChem ID:110634
Structure:
Synonyms:
1-((3-(3,4-Dihydro-5-methyl-4-oxo-7-propylimidazo(5,1-f)-as-triazin-2-yl)-4-ethoxyphenyl)sulfonyl)-4-ethylpiperazine
2-(2-Ethoxy-5-(4-ethylpiperazin-1-yl-1-sulfonyl)phenyl)-5-methyl-7-propyl-
2-(2-Ethoxy-5-(4-ethylpiperazin-1-yl-1-sulfonyl)phenyl)-5-methyl-7-propyl-3H-imidazo(5,1-f)(1,2,4)triazin-4-one
2-[2-ethoxy-5-(4-ethylpiperazin-1-yl)sulfonylphenyl]-5-methyl-7-propyl-1H-imidazo[5,1-f][1,2,4]triazin-4-one
2-{2-ETHOXY-5-[(4-ETHYLPIPERAZIN-1-YL)SULFONYL]PHENYL}-5-METHYL-7-PROPYLIMIDAZO[5,1-F][1,2,4]TRIAZIN-4(1H)-ONE
224785-90-4
BAY 38-9456
BSPBio_002392
DB00862
HSDB 7304
Levitra
Levitra (TN)
LS-111467
NCGC00167533-01
Piperazine, 1-((3-(1,4-dihydro-5-methyl-4-oxo-7-propylimidazo(5,1-f)(1,2,4)triazin-2-yl)-4-ethoxyphenyl)sulfonyl)-4-ethyl-
STK642629
STOCK6S-20068
Vardenafil
VARDENAFIL, LEVITRA
Vardenafil, Vivanza,
VDN
ATC-Codes:
Side-Effects:
Side-EffectFrequency
headache0.095
rhinitis0.060000002
flushing0.06
dyspepsia0.024999999
flu syndrome0.024999999
sinusitis0.02
nausea0.015
dizziness0.014999999
visual field defect0.0010
seizure0.0010
anxiety0.0010
decreased vision0.0010
neuropathy0.0010
vision loss0.0010
loss of hearing0.0010
amnesia0.0010
arrhythmia0.0010
coronary artery disease0.0010
diabetes0.0010
hematemesis0.0010
hematuria0.0010
hemorrhage0.0010
hyperlipidemia0.0010
hypertension0.0010
burning sensation0
palpitations0
dyspnea0
pain0
sinus congestion0
dysphagia0
somnolence0
sweating0
myocardial ischemia0
gastroesophageal reflux0
tinnitus0
diarrhea0
vertigo0
asthenia0
anaphylaxis0
syncope0
transient global amnesia0
photophobia0
blurred vision0
hypotension0
hot flashes0
paresthesia0
eye redness0
myalgia0
arthralgia0
priapism0
photosensitivity0
global amnesia0
ejaculation premature0
feeling abnormal0
liver function tests abnormal0
vomiting0
epistaxis0
esophagitis0
neck pain0
myocardial infarction0
insomnia0
nasal congestion0
erythema0
glaucoma0
conjunctivitis0
back pain0
rash0
edema0
eye pain0
hyperhidrosis0
tachycardia0
angina pectoris0
abdominal pain upper0
postural hypotension0
pharyngitis0
dry mouth0
abdominal pain0
reflux esophagitis0
chest pain0
watery eyes0
hypersensitivity0
pruritus0
sgot increased0
gastritis0

Target

show target details
Uniprot ID:PDE2A_HUMAN
Synonyms:
cGMP-dependent 3',5'-cyclic phosphodiesterase
CGS-PDE
cGSPDE
Cyclic GMP-stimulated phosphodiesterase
EC-Numbers:3.1.4.17
Organism:Homo sapiens
Human
PDB IDs:1Z1L
Structure:
1Z1L

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
-->10000-

References: