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Drug-Target Interaction

Drug

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PubChem ID:10781005
Structure:
Synonyms:
3-(4-oxo-3,5-ditert-butyl-1-cyclohexa-2,5-dienylidene)-1,2,4-thiadiazolidi
CHEBI:118278
CHEMBL279308
CID10781005

Target

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Uniprot ID:PGH2_MOUSE
Synonyms:
COX-2
Cyclooxygenase-2
Glucocorticoid-regulated inflammatory cyclooxygenase
Gripghs
Macrophage activation-associated marker protein P71/73
PES-2
PGH synthase 2
PGHS-2
PHS II
Prostaglandin G/H synthase 2
Prostaglandin H2 synthase 2
Prostaglandin-endoperoxide synthase 2
TIS10 protein
EC-Numbers:1.14.99.1
Organism:Mouse
Mus musculus
PDB IDs:1CVU 1CX2 1DCX 1DD0 1DDX 1PXX 3PGH 4COX 5COX 6COX
Structure:
6COX

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
--18-

References: