Home
Drugs
Targets
Pathways
Ontologies
Cyp450s
Adv.search
Help/FAQ

Drug-Target Interaction

Drug

show drug details
PubChem ID:10631
Structure:
Synonyms:
(1S,8S,11S,15S,2R,10R,14R)-14-acetyl-14-hydroxy-2,8,15-trimethyl-5-oxotetr
(6alpha)-17-hydroxy-6-methylpregn-4-ene-3,20-dione
(6S,8R,9S,10R,13S,14S,17R)-17-acetyl-17-hydroxy-6,10,13-trimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one
17-Hydroxy-6.alpha.-methylprogesterone
17-Hydroxy-6alpha-methyl-pregn-4-ene-3,20-dione
17-Hydroxy-6alpha-methylprogesterone
17.alpha.-Hydroxy-6.alpha.-methylprogesterone
17alpha-Hydroxy-6alpha-methyl-4-pregnene-3,20-dione
17alpha-Hydroxy-6alpha-methylprogesterone
4-08-00-02211 (Beilstein Handbook Reference)
46411_FLUKA
46411_RIEDEL
520-85-4
6-alpha-Methyl-17-alpha-hydroxyprogesterone
6-Dihydromegestrol
6.alpha.-Methyl-17.alpha.-hydroxyprogesterone
6alpha-Methyl-17alpha-hydroxyprogesterone
6alpha-Methyl-4-pregnen-17alpha-ol-3,20-dione
6alpha-Methyl-5-pregnen-17alpha-ol-3,20-dione
AC-14528
AC1L1VM7
Amen
Asconale
BRN 2510965
C07119
C22H32O3
CBP-1011
CCG-101111
CHEBI:6715
Colirest
CPD000058769
Curretab
D08166
DB00603
EINECS 208-298-6
Farlutal
Farlutal inyectable (TN)
g-Farlutal
Hematrol
HMS2052A13
HMS2230B08
HSDB 3114
Hydroxymethylprogesterone
LMST02030176
LS-118713
Lunelle
M6013_SIGMA
MAP
Medroprogesterone Acetate
Medrossiprogesterone
Medrossiprogesterone [DCIT]
Medroxiprogesterona
Medroxiprogesterona [INN-Spanish]
Medroxiprogesteronum
Medroxyprogesteron
Medroxyprogesteron acetate
Medroxyprogesterone
Medroxyprogesterone (INN)
Medroxyprogesterone [INN:BAN]
Medroxyprogesteronum
Medroxyprogesteronum [INN-Latin]
Methylhydroxyprogesterone
MLS000069571
MLS001076098
MPA Gyn 5
NCGC00023064-04
Novo-Medrone
NSC 27408
NSC27408
Pregn-4-ene-3,20-dione, 17-hydroxy-6-alpha-methyl-
Pregn-4-ene-3,20-dione, 17-hydroxy-6-methyl-, (6-alpha)-
Pregn-4-ene-3,20-dione, 17-hydroxy-6-methyl-, (6-alpha)- (9CI)
Pregn-4-ene-3,20-dione, 17-hydroxy-6-methyl-, (6.alpha.)-
Pregn-4-ene-3,20-dione, 17-hydroxy-6-methyl-, (6alpha)-
Pregn-4-ene-3,20-dione, 17-hydroxy-6-methyl-, (6alpha)- (9CI)
Pregn-4-ene-3,20-dione, 17-hydroxy-6.alpha.-methyl-
SAM001246906
SMR000058769
Sodelut G
ST082267
U 8840
UNII-HSU1C9YRES
ZINC05763835
ATC-Codes:
Side-Effects:
Side-EffectFrequency
headache0.28777778
breast pain0.20199999
abdominal pain0.16571428
back pain0.13749999
pain0.13333334
flu syndrome0.11333334
upper respiratory infection0.105
pharyngitis0.105
arthralgia0.093
rhinitis0.08833334
dyspepsia0.08833333
sinusitis0.07833333
insomnia0.07666666
nausea0.07285714
diarrhea0.07
infection0.06715001
flatulence0.06333333
cough0.060000002
dysmenorrhea0.051249996
vaginal moniliasis0.045714285
myalgia0.043666672
vaginal hemorrhage0.04285714
peripheral edema0.04
vaginitis0.037142854
asthenia0.0365
dizziness0.036000002
leg cramps0.034999996
pelvic pain0.030000001
pruritus0.02681818
breast enlargement0.024
anxiety0.0224
rash0.018857142
nervousness0.011666667
muscle spasms0.0010
thyroiditis0.0010
tachycardia0.0010
thrombocytopenia0.0010
supraventricular tachycardia0.0010
fainting0.0010
swelling0.0010
dysphemia0.0010
splenic infarction0.0010
seizures0.0010
scleroderma0.0010
interstitial nephritis0.0010
nephrotic syndrome0.0010
optic neuritis0.0010
osteoporosis0.0010
ovarian cyst0.0010
palpitations0.0010
oligomenorrhea0.0010
papilloedema0.0010
paresthesia0.0010
pericarditis0.0010
ectopic pregnancy0.0010
ptosis0.0010
proteinuria0.0010
benign intracranial hypertension0.0010
purpura0.0010
acute respiratory distress syndrome0.0010
salpingitis0.0010
thrombotic thrombocytopenic purpura0.0010
breast neoplasm0.0010
neuropathy0.0010
bradycardia0.0010
nephrolithiasis0.0010
cervical cancer0.0010
acute psychosis0.0010
rectal bleeding0.0010
vulval abscess0.0010
nerve palsy0.0010
atresia0.0010
vision loss0.0010
allergic reaction0.0010
paranoia0.0010
cerebral ischemia0.0010
hypospadias0.0010
memory loss0.0010
prematurity0.0010
stillbirth0.0010
balance disorder0.0010
paralysis0.0010
osteonecrosis0.0010
sepsis0.0010
parkinsonism0.0010
hepatic failure0.0010
excessive thirst0.0010
chills0.0010
urinary retention0.0010
weight decreased0.0010
vertigo0.0010
vascular disorders0.0010
ulcer0.0010
tremor0.0010
agitation0.0010
acute leukemia0.0010
malaise0.0010
fibroadenoma of breast0.0010
acute porphyria0.0010
vaginal dysplasia0.0010
joint swelling0.0010
dry skin0.0010
muscle weakness0.0010
deep vein thrombosis0.0010
mouth ulceration0.0010
tinnitus0.0010
neoplasms0.0010
anosmia0.0010
trisomy 210.0010
somnolence0.0010
dysarthria0.0010
dyspnea0.0010
eating disorder0.0010
embolism0.0010
anaphylactic reaction0.0010
confusion0.0010
amnesia0.0010
epistaxis0.0010
acute pancreatitis0.0010
facial palsy0.0010
fatigue0.0010
fever0.0010
abscess0.0010
congenital heart defects0.0010
anemia0.0010
dysphagia0.0010
cyst0.0010
ataxia0.0010
blistering0.0010
breast disorders0.0010
bronchospasm0.0010
cachexia0.0010
cerebral hemorrhage0.0010
cerebral infarction0.0010
transient ischemic attack0.0010
cervical dysplasia0.0010
chest pain0.0010
cholangitis0.0010
cholelithiasis0.0010
cleft palate0.0010
hemolytic anemia0.0010
connective tissue disorders0.0010
convulsions0.0010
cardiac disorders0.0010
hypokalemia0.0010
postural hypotension0.0010
hypopituitarism0.0010
hypoglycemia0.0010
spontaneous abortion0.0010
premature menopause0.0010
hyperthyroidism0.0010
hypersensitivity0.0010
salivary gland enlargement0.0010
hypothyroidism0.0010
kidney neoplasm0.0010
fistula0.0010
menorrhagia0.0010
meningioma0.0010
malignant melanoma0.0010
megacolon0.0010
mediastinal disorders0.0010
deformity0.0010
leukocytosis0.0010
hypernatremia0.0010
missed abortion0.0010
diaphragmatic hernia0.0010
hepatomegaly0.0010
hepatitis0.0010
hemorrhage0.0010
endocrine disorders0.0010
blood dyscrasia0.0010
hoarseness0.0010
hydatidiform mole0.0010
hydrocephalus0.0010
angioedema0.00087
jaundice0.00087
thrombophlebitis0.00083
asthma0.00083
galactorrhea0.00083
urticaria0.00083
breast cancer0.00083
nipple discharge0.00083
pulmonary embolus0.00083
cerebrovascular accident0.0008
edema0.0008
melasma0.00071
fibrocystic breast0.00066
increased blood pressure0.00066
porphyria0.00066
erythema nodosum0.00066
myocardial infarction0.00066
gallbladder disease0.00066
erythema multiforme0.00066
venous thrombosis0.00066
ovarian cancer0.00066
migraine0.00066
uterine leiomyoma0.00066
bloating0.0
dementia0.0
spotting0.0
pancreatitis0.0
hypocalcemia0.0
hirsutism0.0
hemangiomas0.0
abdominal cramps0.0
uterine bleeding0.0
vomiting0.0
endometrial cancer0.0
epilepsy0.0
mental depression0.0
ectropion0.0
endometrial hyperplasia0.0
erythema0
neuritis0
muscle cramps0
anorexia0
polyps0
neonatal jaundice0
cervical erosion0
urinary frequency0
breast swelling0
vaginal pruritus0
abdominal distention0
irritability0
emotional lability0
dysuria0
increased sweating0
heartburn0
menstrual irregularity0
weight gain0
vaginal discharge0
menstrual flow0
weakness0
decreased libido0
pain in limb0
bacterial vaginosis0
lump0
leg pain0
urinary tract infection0
smear cervix abnormal0
acne0
alopecia0
varicose vein0
menometrorrhagia0
nasopharyngitis0
cystitis0
hot flashes0
bronchitis0
constipation0
musculoskeletal pain0
cerebral thrombosis0
breast tenderness0

Target

show target details
Uniprot ID:CP2C9_HUMAN
Synonyms:
(R)-limonene 6-monooxygenase
(S)-limonene 6-monooxygenase
(S)-limonene 7-monooxygenase
CYPIIC9
Cytochrome P450 2C9
P-450MP
P450 MP-4/MP-8
P450 PB-1
S-mephenytoin 4-hydroxylase
EC-Numbers:1.14.13.48
1.14.13.49
1.14.13.80
Organism:Homo sapiens
Human
PDB IDs:1OG2 1OG5 1R9O
Structure:
1R9O

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
----

References: