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Drug-Target Interaction

Drug

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PubChem ID:10255
Structure:
Synonyms:
(2S,3S,4S)-3-(Carboxymethyl)-4-(prop-1-en-2-yl)pyrrolidine-2-carboxylic acid
(2S-(2alpha,3beta,4beta))-2-carboxy-4-(1-methylethenyl)-3-pyrrolidineacetic acid
(3S,4R)-3-(carboxymethyl)-4-(prop-1-en-2-yl)-L-proline
(3S,4S)-3-(carboxymethyl)-4-prop-1-en-2-yl-L-proline
1p1n
2-Carboxy-3-carboxymethyl-4-isopropenylpyrrolidine
2-Carboxy-4-(1-methylethenyl)-3-pyrrolidineacetic Acid
2-Carboxy-4-isopropenyl-3-pyrrolidineacetic acid
3-Pyrrolidineacetic acid, 2-carboxy-4-(1-methylethenyl)-,
3-Pyrrolidineacetic acid, 2-carboxy-4-(1-methylethenyl)-, (2S-(2-alpha,3-beta,4-beta))-
3-Pyrrolidineacetic acid, 2-carboxy-4-(1-methylethenyl)-, (2S-(2-alpha,3-beta,4-beta))- (9CI)
3-Pyrrolidineacetic acid, 2-carboxy-4-(1-methylethenyl)-, (2S-(2alpha,3beta,4beta))-
3-Pyrrolidineacetic acid, 2-carboxy-4-isopropenyl-
4-22-00-01523 (Beilstein Handbook Reference)
487-79-6
59905-23-6
Acide kainique
Acide kainique [INN-French]
Acido kainico
Acido kainico [INN-Spanish]
Acidum kainicum
Acidum kainicum [INN-Latin]
alpha- Kainic acid
alpha-Kainic acid
Biomol-NT_000217
BPBio1_001306
BRN 0086660
C10H15NO4
C12819
CHEBI:31746
Digenic acid
Digenin
Digensaeure
EU-0100656
Helminal
K0250_SIGMA
KAI
Kainate
KAINIC ACID
Kainic acid monohydrate
Kainic acid [INN:JAN]
Kainsaeure
L-alpha-Kainic acid
L-proline, 3-(carboxymethyl)-4-(1-methylethenyl)-, (3S,4S)-
Lopac0_000656
LS-137114
MLS001074661
NCGC00024504-02
NCGC00024504-03
NCGC00024504-04
NCGC00024504-05
NCGC00024504-06
nchembio881-comp3
NSC 136038
NSC136038
rel-(3R,4R)-3-(carboxymethyl)-4-isopropenyl-D-proline
SMR000471885
UPCMLD-DP146
UPCMLD-DP146:001
UPCMLD-DP146:002

Target

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Uniprot ID:GRIA2_RAT
Synonyms:
AMPA-selective glutamate receptor 2
GluR-2
GluR-B
GluR-K2
Glutamate receptor 2
Glutamate receptor ionotropic, AMPA 2
EC-Numbers:-
Organism:Rat
Rattus norvegicus
PDB IDs:1FTJ 1FTK 1FTL 1FTM 1FTO 1FW0 1GR2 1LB8 1LB9 1LBB 1LBC 1M5B 1M5C 1M5D 1M5E 1M5F 1MM6 1MM7 1MQD 1MQG 1MQH 1MQI 1MQJ 1MS7 1MXU 1MXV 1MXW 1MXX 1MXY 1MXZ 1MY0 1MY1 1MY2 1MY3 1MY4 1N0T 1NNK 1NNP 1P1N 1P1O 1P1Q 1P1U 1P1W 1SYH 1SYI 1WVJ 1XHY 2AIX 2AL4 2AL5 2ANJ 2CMO 2GFE 2I3V 2I3W 2P2A 2UXA 3B6Q 3B6T 3B6W 3B7D 3BBR 3BFT 3BFU 3BKI 3DP6 3H03 3H06 3H5V 3H5W 3H6T 3H6U 3H6V 3H6W 3IJO 3IJX 3IK6 3IL1 3ILT 3ILU
Structure:
3ILU

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
3690---
---380000

References: