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Drug-Target Interaction

Drug

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PubChem ID:10255
Structure:
Synonyms:
(2S,3S,4S)-3-(Carboxymethyl)-4-(prop-1-en-2-yl)pyrrolidine-2-carboxylic acid
(2S-(2alpha,3beta,4beta))-2-carboxy-4-(1-methylethenyl)-3-pyrrolidineacetic acid
(3S,4R)-3-(carboxymethyl)-4-(prop-1-en-2-yl)-L-proline
(3S,4S)-3-(carboxymethyl)-4-prop-1-en-2-yl-L-proline
1p1n
2-Carboxy-3-carboxymethyl-4-isopropenylpyrrolidine
2-Carboxy-4-(1-methylethenyl)-3-pyrrolidineacetic Acid
2-Carboxy-4-isopropenyl-3-pyrrolidineacetic acid
3-Pyrrolidineacetic acid, 2-carboxy-4-(1-methylethenyl)-,
3-Pyrrolidineacetic acid, 2-carboxy-4-(1-methylethenyl)-, (2S-(2-alpha,3-beta,4-beta))-
3-Pyrrolidineacetic acid, 2-carboxy-4-(1-methylethenyl)-, (2S-(2-alpha,3-beta,4-beta))- (9CI)
3-Pyrrolidineacetic acid, 2-carboxy-4-(1-methylethenyl)-, (2S-(2alpha,3beta,4beta))-
3-Pyrrolidineacetic acid, 2-carboxy-4-isopropenyl-
4-22-00-01523 (Beilstein Handbook Reference)
487-79-6
59905-23-6
Acide kainique
Acide kainique [INN-French]
Acido kainico
Acido kainico [INN-Spanish]
Acidum kainicum
Acidum kainicum [INN-Latin]
alpha- Kainic acid
alpha-Kainic acid
Biomol-NT_000217
BPBio1_001306
BRN 0086660
C10H15NO4
C12819
CHEBI:31746
Digenic acid
Digenin
Digensaeure
EU-0100656
Helminal
K0250_SIGMA
KAI
Kainate
KAINIC ACID
Kainic acid monohydrate
Kainic acid [INN:JAN]
Kainsaeure
L-alpha-Kainic acid
L-proline, 3-(carboxymethyl)-4-(1-methylethenyl)-, (3S,4S)-
Lopac0_000656
LS-137114
MLS001074661
NCGC00024504-02
NCGC00024504-03
NCGC00024504-04
NCGC00024504-05
NCGC00024504-06
nchembio881-comp3
NSC 136038
NSC136038
rel-(3R,4R)-3-(carboxymethyl)-4-isopropenyl-D-proline
SMR000471885
UPCMLD-DP146
UPCMLD-DP146:001
UPCMLD-DP146:002

Target

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Uniprot ID:GRIA2_HUMAN
Synonyms:
AMPA-selective glutamate receptor 2
GluR-2
GluR-B
GluR-K2
Glutamate receptor 2
Glutamate receptor ionotropic, AMPA 2
EC-Numbers:-
Organism:Homo sapiens
Human
PDB IDs:2WJW 2WJX
Structure:
2WJX

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
12200---
12221---
---10570

References: