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Drug-Target Interaction

Drug

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PubChem ID:10100
Structure:
Synonyms:
()-1,2-diphenyl-2-propionoxy-3-methyl-4-dimethylaminobutane
()-4-dimethylamino-1,2-diphenyl-3-methyl-2-propionyloxybutane
(+)-1,2-Diphenyl-2-propionoxy-3-methyl-4-dimethylaminobutane
(+)-4-Dimethylamino-1,2-diphenyl-3-methyl-2-propionyloxybutane
(1S,2R)-1-benzyl-3-(dimethylamino)-2-methyl-1-phenylpropyl propanoate
(D)-PROPOXYPHENE
(S)-alpha-(2-(Dimethylamino)-1-methylethyl)-alpha-phenylbenzeneethanol
(S)-alpha-(2-(Dimethylamino)-1-methylethyl)-alpha-phenylbenzeneethanol propanoate
2-Butanol, 4-(dimethylamino)-3-methyl-1,2-diphenyl-, propionate (ester), (2S,3R)-
2-butanol, 4-(dimethylamino)-3-methyl-1,2-diphenyl-, propionate, ()-
2-Butanol, 4-(dimethylamino)-3-methyl-1,2-diphenyl-, propionate, (+)-
21086-94-2
3818-94-8
4-Dimethylamino-3-methyl-1,2-diphenyl-2-propoxybutane
469-62-5
Algafan
alpha-()-4-dimethylamino-1,2-diphenyl-3-methyl-2-butanol propionate ester
alpha-()-4-dimethylamino-1,2-diphenyl-3-methyl-2-propionoxybutane
alpha-(+)-4-Dimethylamino-1,2-diphenyl-3-methyl-2-butanol propionate ester
alpha-(+)-4-Dimethylamino-1,2-diphenyl-3-methyl-2-propionoxybutane
alpha-4-Dimethylamino-1,2-diphenyl-3-methyl-2-butanol propionate
alpha-D-4-Dimethylamino-3-methyl-1,2-diphenyl-2-butanol propionate
alpha-D-4-Dimethylamino-3-methyl-1,2-diphenyl-2-butanol-propionat
alpha-D-4-Dimethylamino-3-methyl-1,2-diphenyl-2-butanol-propionat [German]
Antalvic
Benzeneethanol, alpha-((1R)-2-(dimethylamino)-1-methylethyl)-alpha-phenyl-, propanoate (ester), (alphaS)-
Benzeneethanol, alpha-(2-(dimethylamino)-1-methylethyl)-alpha-phenyl-, propanoate (ester), (S-(R*,S*))-
Bulk dextropropoxyphene (non-dosage forms)
C07406
C22H29NO2
CHEBI:51173
d-Propoxyphene
Darvocet
Darvon
DEA No. 9273
Depromic
Destropropossifene
Destropropossifene [DCIT]
Dextropropoxifeno
Dextropropoxifeno [INN-Spanish]
Dextropropoxyphen
Dextropropoxyphene
Dextropropoxyphene [INN:BAN]
Dextropropoxyphenum
Dextropropoxyphenum [INN-Latin]
Dextroproxifeno
Dextroproxifeno [Spanish]
EINECS 207-420-5
Femadol
HSDB 3175
Levopropoxyphene
LS-46517
Propoxyphene
propoxyphene, ()-
Propoxyphene, (+)-
Proxagesic
Proxyphen
SK 65
ATC-Codes:
Side-Effects:
Side-EffectFrequency
myopathy0
elation0
euphoria0
headache0
lightheadedness0
somnolence0
abdominal pain0
hallucinations0
jaundice0
dizziness0
vomiting0
weakness0
convulsions0
constipation0
liver function tests abnormal0
nausea0
dysphoria0

Target

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Uniprot ID:CP2C9_HUMAN
Synonyms:
(R)-limonene 6-monooxygenase
(S)-limonene 6-monooxygenase
(S)-limonene 7-monooxygenase
CYPIIC9
Cytochrome P450 2C9
P-450MP
P450 MP-4/MP-8
P450 PB-1
S-mephenytoin 4-hydroxylase
EC-Numbers:1.14.13.48
1.14.13.49
1.14.13.80
Organism:Homo sapiens
Human
PDB IDs:1OG2 1OG5 1R9O
Structure:
1R9O

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
----

References: