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Drug Details

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Name:DORZOLAMIDE
PubChem ID:92087
Pathway:Show KEGG pathways
InChI:InChI=1/C10H16N2O4S3/c1-3-12-8-4-6(2)18(13,14)10-7(8)5-9(17-10)19(11,15)16/h5-6,8,12H,3-4H2,1-2H3,(H2,11,15,16)/t6-,8-/m1/s1/f/h11H2
SMILES:CCN[C@@H]1(C[C@H](C)S(c2c1cc(s2)S(N)(=O)=O)(=O)=O)

Properties:
Formula:C10H16N2O4S3Atoms:19
Molecular Weight:324.44Rotatable Bonds:3
H-bond Acceptors:6H-bond Donors:0
logP:3.8648
Targets:
Synonyms:
120279-96-1
4H-Thieno(2,3-b)thiopyran-2-sulfonamide,
4H-Thieno(2,3-b)thiopyran-2-sulfonamide, 4-(ethylamino)-5,6-dihydro-6-methyl-, 7,7-dioxide, (4S,6S)-
4H-Thieno(2,3-b)thiopyran-2-sulfonamide, 4-(ethylamino)-5,6-dihydro-6-methyl-, 7,7-dioxide, (4S-trans)-
4S,6S-Dorzolamide
C10H16N2O4S3
DORZOLAMIDE
Dorzolamide [INN:BAN]
dorzolamide, (trans)-isomer
LS-172441
LS-172442
sulfonamide 5
ATC-Codes:
Side-Effects:
Side-EffectFrequency
urticaria0.0010
myopia0.0010
allergic reactions0.0010
contact dermatitis0.0010
dizziness0.0010
dry mouth0.0010
paresthesia0.0010
epistaxis0.0010
hypersensitivity0.0010
keratitis0.0010
angioedema0.0010
bronchospasm0.0010
urolithiasis0.0010
pruritus0.0005
pain0.0005
weight loss0.0
weakness0.0
agranulocytosis0.0
sweating0.0
fever0.0
vertigo0.0
mental depression0.0
hypoglycemia0.0
hepatomegaly0.0
hyperglycemia0.0
arthralgia0.0
sore throat0.0
purpura0.0
rash0.0
ischemic colitis0.0
extremity pain0.0
skin irritation0.0
arterial insufficiency0.0
ptosis0
psoriasis0
syncope0
pulmonary edema0
pharyngitis0
retroperitoneal fibrosis0
sinusitis0
visual field defect0
cerebrovascular accident0
tinnitus0
erythema0
respiratory failure0
insomnia0
cerebral ischemia0
memory loss0
bradycardia0
blurred vision0
urinary tract infection0
dry eyes0
eye redness0
back pain0
eye pain0
cataract0
emotional lability0
vomiting0
photophobia0
vitreous detachment0
upper respiratory tract infection0
claudication0
palpitations0
confusion0
conjunctivitis0
cough0
decreased libido0
diarrhea0
diplopia0
somnolence0
dyspepsia0
chest pain0
bronchitis0
alopecia0
anaphylaxis0
angina pectoris0
anorexia0
anxiety0
arrhythmia0
asthenia0
blepharitis0
dyspnea0
edema0
iridocyclitis0
lupus0
myasthenia gravis0
myocardial infarction0
nasal congestion0
nausea0
nervousness0
nightmares0
influenza0
impotence0
fatigue0
hallucinations0
headache0
cardiac arrest0
heart block0
heart failure0
hypertension0
hypotension0
abdominal pain0