Drug Details

Name:

Tosyllysine chloromethyl ketone

PubChem ID:

73094

Pathway:

Show KEGG pathways

InChI:

InChI=1/C14H21ClN2O3S/c1-11-5-7-12(8-6-11)21(19,20)17-13(14(18)10-15)4-2-3-9-16/h5-8,13,17H,2-4,9-10,16H2,1H3/t13-/m0/s1

SMILES:

Cc1ccc(cc1)S(N[C@H](CCCCN)C(CCl)=O)(=O)=O

Properties:

Formula:	C14H21ClN2O3S	Atoms:	21
Molecular Weight:	332.846	Rotatable Bonds:	9
H-bond Acceptors:	5	H-bond Donors:	0
logP:	3.7508

Targets:

Name	Uniprot ID	Source	References	Interaction
Caspase	ICE_DROME	PROMISCUOUS	PMID 11746380	shows
Caspase-3	CASP3_HUMAN	PROMISCUOUS	PMID 18980241	shows
Caspase-3	CASP3_RAT	PROMISCUOUS	PMID 11746380	shows
Prostaglandin G/H synthase 2	PGH2_HUMAN	PROMISCUOUS	PMID 9568691	shows
Serine endopeptidases	Q0VS35_ALCBS	PROMISCUOUS	PMID 9894608	shows

enlarge table

Synonyms:

(-)-1-Chloro-3-tosylamido-7-amino-2-heptanone

2364-87-6

4238-41-9

AC1L2J9B

AIDS-042745

AIDS042745

alpha-Tosyl-L-lysylchloromethyl ketone

AR-1K3052

Benzenesulfonamide, N-((1S)-5-amino-1-(chloroacetyl)pentyl)-4-methyl-

Benzenesulfonamide, N-(5-amino-1-(chloroacetyl)pentyl)-4-methyl-, (S)-

BRN 2885388

C00896

CCG-205254

CHEMBL466465

CK004

DB08603

Lopac-T-7254

Lopac0_001180

LS-154095

N-alpha-p-Tosyl-L-lysine chloromethyl ketone

N-alpha-Tosyl-L-lysyl-chloromethylketone

n-[(3s)-7-amino-1-chloro-2-oxoheptan-3-yl]-4-methylbenzenesulfonamide

N.alpha.-pTosyl-L-lysine chloromethylketone

Na-p-Tosyl-L-lysine chloromethyl ketone hydrochloride

NCGC00016045-01

NCGC00162359-01

NCGC00162359-02

p-Toluenesulfonamide, N-(5-amino-1-(chloroacetyl)pentyl)-, L-

TLCK

Tos-Lys-CH2Cl

Tosyl-K-CMK

Tosyl-L-lysine chloromethyl ketone

Tosyl-Lys-CMK

Tosyllysine chloromethyl ketone

Tosyllysyl chloromethyl ketone

enlarge table