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Name:Voriconazole
PubChem ID:71616
Pathway:Show KEGG pathways
InChI:InChI=1/C16H14F3N5O/c1-10(15-14(19)5-20-7-22-15)16(25,6-24-9-21-8-23-24)12-3-2-11(17)4-13(12)18/h2-5,7-10,25H,6H2,1H3/t10-,16+/m0/s1
SMILES:C[C@@H](c1c(cncn1)F)[C@](Cn1cncn1)(c1ccc(cc1F)F)O

Properties:
Formula:C16H14F3N5OAtoms:25
Molecular Weight:349.31Rotatable Bonds:5
H-bond Acceptors:8H-bond Donors:0
logP:2.1769
Targets:
Synonyms:
(2R,3S)-2-(2,4-difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1,2,4-triazol-1-yl)butan-2-ol
(alphaR,betaS)-alpha-(2,4-Difluorophenyl)-5-fluoro-beta-methyl-alpha-(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanol
(R-(R*,S*))-alpha-(2,4-difluorophenyl)-5-fluoro-beta-methyl-alpha-(1H-1,2,
(R-(R*,S*))-alpha-(2,4-difluorophenyl)-5-fluoro-beta-methyl-alpha-(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanol
137234-62-9
4-Pyrimidineethanol, alpha-(2,4-difluorophenyl)-5-fluoro-beta-methyl-alpha-(1H-1,2,4-triazol-1-ylmethyl)-, (R-(R*,S*))-
AIDS-045515
AIDS045515
C07622
C102790
CHEBI:10023
CPD000466350
D00578
DB00582
DRG-0301
LS-181799
MLS000759464
MLS001424082
Pfizer brand of voriconazole
SAM001246664
SMR000466350
TL8000858
UK 109,496
UK 109496
UK-109,496
UK-109496
VCZ
Vfend
Vfend (TN)
Vfend, Voriconazole
Voriconazole
Voriconazole (JAN/USAN/INN)
Voriconazole [USAN:BAN:INN]
Voriconazole [USAN:INN:BAN]
VRC
ZINC00014864
ATC-Codes:
Side-Effects:
Side-EffectFrequency
syncope0.0010
thrombotic thrombocytopenic purpura0.0010
purpura0.0010
pulmonary embolus0.0010
lung edema0.0010
psychosis0.0010
psoriasis0.0010
pruritus0.0010
proctitis0.0010
supraventricular extrasystoles0.0010
pneumonia0.0010
pleural effusion0.0010
phlebitis0.0010
respiratory distress syndrome0.0010
retina0.0010
retinal hemorrhage0.0010
sweating0.0010
cerebrovascular accident0.0010
stomatitis0.0010
stomach ulcer0.0010
stevens - johnson syndrome0.0010
enlarged spleen0.0010
sinusitis0.0010
convulsion0.0010
visual field defect0.0010
scleritis0.0010
rhinitis0.0010
retinitis0.0010
pharyngitis0.0010
petechia0.0010
nystagmus0.0010
night blindness0.0010
neuralgia0.0010
nephrosis0.0010
myocardial infarction0.0010
fungal infection0.0010
myopathy0.0010
metrorrhagia0.0010
melena0.0010
melanosis0.0010
lymphangitis0.0010
discoid lupus erythematosis0.0010
optic atrophy0.0010
optic neuritis0.0010
osteomalacia0.0010
peritonitis0.0010
periodontitis0.0010
pelvic pain0.0010
paresthesia0.0010
papilledema0.0010
pancytopenia0.0010
pancreatitis0.0010
palpitation0.0010
pain0.0010
otitis externa0.0010
osteoporosis0.0010
bone necrosis0.0010
liver disease0.0010
allergic reaction0.0010
dry eyes0.0010
rectal hemorrhage0.0010
bigeminy0.0010
sepsis0.0010
color blindness0.0010
hypoxia0.0010
myalgia0.0010
intestinal ulcer0.0010
esophageal ulcer0.0010
deep thrombophlebitis0.0010
skin dry0.0010
eye pain0.0010
parotid gland enlargement0.0010
photosensitivity0.0010
bradycardia0.0010
hypoacusis0.0010
pseudomembranous colitis0.0010
insomnia0.0010
cerebral ischemia0.0010
cardiomyopathy0.0010
duodenal ulcer perforation0.0010
hyperuricemia0.0010
kidney pain0.0010
dementia0.0010
lymphadenopathy0.0010
vision loss0.0010
neuropathy0.0010
substernal chest pain0.0010
bone pain0.0010
ventricular tachycardia0.0010
ventricular fibrillation0.0010
uveitis0.0010
uterine hemorrhage0.0010
urticaria0.0010
urinary tract infection0.0010
urinary incontinence0.0010
uremia0.0010
tremor0.0010
tinnitus0.0010
thrombophlebitis0.0010
thrombocytopenia0.0010
vertigo0.0010
voice alteration0.0010
dry mouth0.0010
abnormal liver function tests0.0010
hypomagnesemia0.0010
hypermagnesemia0.0010
vaginal hemorrhage0.0010
av block complete0.0010
mouth ulceration0.0010
hypophosphatemia0.0010
peripheral edema0.0010
agitation0.0010
hepatic failure0.0010
encephalopathy0.0010
urinary retention0.0010
supraventricular tachycardia0.0010
leukopenia0.0010
encephalitis0.0010
drug eruption0.0010
exfoliative dermatitis0.0010
delirium0.0010
dysphagia0.0010
libido decreased0.0010
deafness0.0010
cystitis0.0010
cough0.0010
corneal opacity0.0010
constipation0.0010
conjunctivitis0.0010
confusion0.0010
contact dermatitis0.0010
diabetes insipidus0.0010
diarrhea0.0010
edema0.0010
eczema0.0010
ecchymosis0.0010
ear pain0.0010
dysuria0.0010
dyspnea0.0010
dyspepsia0.0010
dysmenorrhea0.0010
duodenitis0.0010
somnolence0.0010
dizziness0.0010
diplopia0.0010
coma0.0010
cholelithiasis0.0010
arthralgia0.0010
arrhythmias0.0010
anxiety0.0010
anorexia0.0010
angioedema0.0010
hemolytic anemia0.0010
aplastic anemia0.0010
anemia0.0010
amnesia0.0010
alopecia0.0010
albuminuria0.0010
agranulocytosis0.0010
arthritis0.0010
ascites0.0010
aspergillosis0.0010
cholecystitis0.0010
chest pain0.0010
cerebral hemorrhage0.0010
cellulitis0.0010
candidiasis0.0010
bundle branch block0.0010
blepharitis0.0010
bacterial infection0.0010
back pain0.0010
atrial fibrillation0.0010
ataxia0.0010
asthenia0.0010
abdominal pain0.0010
leg cramps0.0010
hypertension0.0010
hypernatremia0.0010
hyperkalemia0.0010
hyperglycemia0.0010
hypercholesteremia0.0010
hypercalcemia0.0010
hydronephrosis0.0010
herpes simplex0.0010
enlarged liver0.0010
hepatitis0.0010
hepatic coma0.0010
hemorrhage0.0010
hyperthyroidism0.0010
hypocalcemia0.0010
keratoconjunctivitis0.0010
keratitis0.0010
jaundice0.0010
intestinal perforation0.0010
flu syndrome0.0010
infections0.0010
impotence0.0010
hypothyroidism0.0010
postural hypotension0.0010
hypotension0.0010
hyponatremia0.0010
hypoglycemia0.0010
hemoptysis0.0010
hematuria0.0010
glossitis0.0010
flatulence0.0010
flank pain0.0010
rash0.0010
esophagitis0.0010
erythema multiforme0.0010
epistaxis0.0010
grand mal convulsion0.0010
epididymitis0.0010
toxic epidermal necrolysis0.0010
eosinophilia0.0010
endocarditis0.0010
furunculosis0.0010
gastroenteritis0.0010
gastrointestinal hemorrhage0.0010
hematemesis0.0010
congestive heart failure0.0010
cardiomegaly0.0010
heart arrest0.0010
gingivitis0.0010
granuloma0.0010
graft versus host reaction0.0010
glycosuria0.0010
gum hemorrhage0.0010
hypokalemia0.0008
acute renal failure0.0005
headache0.0
fever0.0
hallucinations0.0
tachycardia0.0
sore throat0
abnormal vision0
vomiting0
malaise0
depersonalization0
sgot increased0
photophobia0
alkaline phosphatase increased0
chills0
blurred vision0
elevated liver function tests0
nausea0
bilirubinemia0
euphoria0