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Drug Details

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Name:Atorvastatin
PubChem ID:60823
Pathway:Show KEGG pathways
InChI:InChI=1/C33H35FN2O5/c1-21(2)31-30(33(41)35-25-11-7-4-8-12-25)29(22-9-5-3-6-10-22)32(23-13-15-24(34)16-14-23)36(31)18-17-26(37)19-27(38)20-28(39)40/h3-16,21,26-27,37-38H,17-20H2,1-2H3,(H,35,41)(H,39,40)/t26-,27-/m1/s1/f/h35,39H
SMILES:CC(C)c1c(c(c2ccccc2)c(c2ccc(cc2)F)n1CC[C@@H](C[C@@H](CC(O)=O)O)O)C(Nc1ccccc1)=O

Properties:
Formula:C33H35FN2O5Atoms:43
Molecular Weight:558.64Rotatable Bonds:13
H-bond Acceptors:7H-bond Donors:0
logP:6.3866
Targets:
NameUniprot IDSourceReferencesInteraction
3-hydroxy-3-methylglutaryl-coenzyme A reductaseHMDH_HUMANSuperTargetPMID 007621974shows
AngiotensinogenANGT_HUMANDrugBank-shows
Apolipoprotein B-100APOB_HUMANDrugBank-shows
C-C motif chemokine 2CCL2_HUMANDrugBank-shows
C-reactive proteinCRP_HUMANDrugBank-shows
CD40 ligandCD40L_HUMANDrugBank-shows
Collagen alpha-1(XIII) chainCODA1_HUMANDrugBank-shows
Cyclooxygenase 2Q99MH2_MOUSEPROMISCUOUSPMID 18469150shows
Cytochrome P450Q7Z448_HUMANSuperTargetPMID 012485953shows
Cytochrome P450Q86SK2_HUMANSuperTargetPMID 012485953shows
Cytochrome P450Q86SK3_HUMANSuperTargetPMID 012485953shows
Cytochrome P450 2C8CP2C8_HUMANSuperCypPMID 15998357shows
Cytochrome P450 3A4CP3A4_HUMANPROMISCUOUSPMID 16388406shows
Cytochrome P450 3A5CP3A5_HUMANSuperCypPMID 16388406shows
Cytochrome P450 3A7CP3A7_HUMANSuperCyp-shows
Cytochrome P450 CYP3A4Q9BZM0_HUMANSuperTargetPMID 012485953shows
Cytochrome P450 family 3 subfamily A polypeptide 4Q6GRK0_HUMANSuperTargetPMID 012485953shows
Dipeptidyl peptidase 4DPP4_PIGBindingDB-shows
DNA replication licensing factor MCM6MCM6_HUMANSuperTargetPMID 12591091shows
DNA replication licensing factor MCM7MCM7_HUMANSuperTargetPMID 12591091shows
Dual oxidase 1DUOX1_RATPROMISCUOUSPMID 11408394shows
Dual oxidase 2DUOX2_RATPROMISCUOUSPMID 11408394shows
Low-density lipoprotein receptorLDLR_HUMANPROMISCUOUSPMID 11735125shows
Neuronal nitric-oxide synthase isoform muO75713_HUMANPROMISCUOUSPMID 11735125shows
Nitric oxide synthaseQ62710_RATPROMISCUOUSPMID 11408394shows
Nitric oxide synthase, brainNOS1_HUMANPROMISCUOUSPMID 11735125shows
Nitric oxide synthase, brainNOS1_MOUSEPROMISCUOUSPMID 19131647shows
Nitric oxide synthase, endothelialNOS3_HUMANPROMISCUOUSPMID 11735125shows
Nitric oxide synthase, endothelialNOS3_MOUSEPROMISCUOUSPMID 19131647shows
Nitric oxide synthase, inducibleNOS2_HUMANPROMISCUOUSPMID 11735125shows
Nitric oxide synthase, inducibleNOS2_MOUSEPROMISCUOUSPMID 19131647shows
Peroxisome proliferator-activated receptor alphaPPARA_HUMANDrugBank-shows
Peroxisome proliferator-activated receptor gammaPPARG_HUMANDrugBank-shows
Plasminogen activator inhibitor 1PAI1_HUMANDrugBank-shows
Serum paraoxonase/arylesterase 1PON1_HUMANDrugBank-shows
SLCO1B1 proteinQ6NSF9_HUMANSuperTargetPMID 014531725shows
SLCO1B1 proteinQ7Z4M3_HUMANSuperTargetPMID 014531725shows
Solute carrier organic anion transporter family member 1B1SO1B1_HUMANSuperTargetPMID 014531725shows
Transforming protein RhoARHOA_HUMANDrugBank-shows
Tumor necrosis factorTNFA_HUMANDrugBank-shows
Vascular endothelial growth factor AVEGFA_HUMANDrugBank-shows
Synonyms:
(3R,5R)-7-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-propan-2-ylpyrrol-1-yl]-3,5-dihydroxyheptanoic acid
(3R,5R)-7-[3-(anilinocarbonyl)-5-(4-fluorophenyl)-2-isopropyl-4-phenyl-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoic acid
(3R,5R)-7-[3-(anilinocarbonyl)-5-(4-fluorophenyl)-4-phenyl-2-(propan-2-yl)-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoic acid
(betaR,deltaR)-2-(p-Fluorophenyl)-beta,delta-dihydroxy-5-isopropyl-3-pheny
(betaR,deltaR)-2-(p-Fluorophenyl)-beta,delta-dihydroxy-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)pyrrole-1-heptanoic acid
(R-(R*,R*))-2-(4-Fluorophenyl)-beta,delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4-((phenylamino)carbonyl)-1H-pyrrole-1-heptanoic acid
134523-00-5
134523-03-8
1H-Pyrrole-1-heptanoic acid, 2-(4-fluorophenyl)-beta,delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4-((phenylamino)carbonyl)-, (R-(R*,R*))-
7-[2-(4-FLUORO-PHENYL)-5-ISOPROPYL-3-PHENYL-4-PHENYLCARBAMOYL-PYRROL-1-YL]- 3,5-DIHYDROXY-HEPTANOIC ACID
7-[2-(4-FLUORO-PHENYL)-5-ISOPROPYL-3-PHENYL-4-PHENYLCARBAMOYL-PYRROL-1-YL]-3,5-DIHYDROXY-HEPTANOIC ACID
Atorvastatin
Atorvastatin (INN)
Atorvastatin (R-(R*,R*))
Atorvastatin calcium
Atorvastatin [INN:BAN]
atrovastin
C06834
C33H35FN2O5
Cardyl
CCRIS 7159
CHEBI:39548
CI 981
D07474
DB01076
HSDB 7039
Lipitor
Lipitor (TN)
Liprimar
LS-136975
NCGC00159458-02
Sortis
Sortis (TN)
Sotis
Torvast
Totalip
Tozalip
Tulip
Xavator
ATC-Codes: