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Drug Details

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Name:Triphosphopyridine nucleotide
PubChem ID:5886
Pathway:Show KEGG pathways
InChI:InChI=1/C21H28N7O17P3/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(44-46(33,34)35)14(30)11(43-21)6-41-48(38,39)45-47(36,37)40-5-10-13(29)15(31)20(42-10)27-3-1-2-9(4-27)18(23)32/h1-4,7-8,10-11,13-16,20-21,29-31H,5-6H2,(H7-,22,23,24,25,32,33,34,35,36,37,38,39)/p+1/t10-,11-,13-,14-,15-,16-,20-,21-/m1/s1/fC21H29N7O17P3/h33-34,36,38H,22-23H2/q+1
SMILES:c1cc(c[n+](c1)[C@H]1([C@H]([C@H]([C@@H](COP(O)(=O)OP(O)(=O)OC[C@H]2[C@H]([C@H]([C@@H](n3cnc4c(N)ncnc34)O2)OP(O)(O)=O)O)O1)O)O))C(N)=O

Properties:
Formula:C21H29N7O17P3Atoms:56
Molecular Weight:744.413Rotatable Bonds:13
H-bond Acceptors:22H-bond Donors:0
logP:-1.6174
Targets:
NameUniprot IDSourceReferencesInteraction
2,4-dienoyl-CoA reductase [NADPH]FADH_ECOLIDrugBank-shows
2,4-dienoyl-CoA reductase, mitochondrialDECR_HUMANDrugBank-shows
2,5-diketo-D-gluconic acid reductase ADKGA_CORSCDrugBank-shows
3-alpha-hydroxysteroid dehydrogenaseDIDH_RATDrugBank-shows
3-hydroxy-3-methylglutaryl-coenzyme A reductaseHMDH_HUMANDrugBank-shows
3-oxoacyl-[acyl-carrier-protein] reductaseFABG_ECOLIDrugBank-shows
3-oxoacyl-[acyl-carrier-protein] reductase 3, chloroplasticFABG3_BRANADrugBank-shows
ADP-L-glycero-D-manno-heptose-6-epimeraseHLDD_ECOLIDrugBank-shows
Alcohol dehydrogenase [NADP+]AK1A1_PIGDrugBank-shows
Alcohol dehydrogenase, iron-containingQ9X022_THEMADrugBank-shows
Aldo-keto reductase family 1 member C1AK1C1_HUMANDrugBank-shows
Aldo-keto reductase family 1 member C2AK1C2_HUMANDrugBank-shows
Aldo-keto reductase family 1 member C3AK1C3_HUMANDrugBank-shows
Aldose reductaseALDR_HUMANDrugBank-shows
Aldose reductaseALDR_PIGDrugBank-shows
Aldose reductase-related protein 2ALD2_CRIGRDrugBank-shows
Aldose reductase-related protein 2ALD2_MOUSEDrugBank-shows
Aspartate-semialdehyde dehydrogenaseDHAS_HAEINDrugBank-shows
Bifunctional protein mdtAMTDA_METEADrugBank-shows
C-1-tetrahydrofolate synthase, cytoplasmicC1TC_HUMANDrugBank-shows
Carbonyl reductase [NADPH] 2CBR2_MOUSEDrugBank-shows
Conserved proteinO27779_METTHDrugBank-shows
Corticosteroid 11-beta-dehydrogenase isozyme 1DHI1_HUMANDrugBank-shows
Dehydrogenase/reductase SDR family member 11DHR11_HUMANDrugBank-shows
Dihydrofolate reductaseDYR_ECOLIDrugBank-shows
Dihydrofolate reductaseDYR_HUMANDrugBank-shows
Dihydrofolate reductaseDYR_PNECADrugBank-shows
Estradiol 17-beta-dehydrogenase 1DHB1_HUMANDrugBank-shows
Ferredoxin--NADP reductaseFENR_ANASODrugBank-shows
Ferredoxin--NADP reductaseFENR_ANASPDrugBank-shows
Ferredoxin--NADP reductase, leaf isozyme, chloroplasticFENR1_PEADrugBank-shows
Flavin reductaseBLVRB_HUMANDrugBank-shows
GDP-L-fucose synthetaseFCL_ECOLIDrugBank-shows
General stress protein 69GS69_BACSUDrugBank-shows
Glucose-6-phosphate 1-dehydrogenaseG6PD_HUMANDrugBank-shows
Glucose-6-phosphate 1-dehydrogenaseG6PD_LEUMEDrugBank-shows
Glucose-6-phosphate 1-dehydrogenaseG6PD_RATPROMISCUOUSPMID 22033shows
Glutamate dehydrogenaseO60995_TRYCRPROMISCUOUSPMID 39772shows
Glutamate dehydrogenaseO60996_TRYCRPROMISCUOUSPMID 39772shows
Glyceraldehyde-3-phosphate dehydrogenaseG3P_METFEDrugBank-shows
Glyceraldehyde-3-phosphate dehydrogenase (NADP+)O57693_THETEDrugBank-shows
Isocitrate dehydrogenase [NADP]IDH_AZOVIDrugBank-shows
Isocitrate dehydrogenase [NADP]IDH_ECOLIDrugBank-shows
Isocitrate dehydrogenase [NADP] cytoplasmicIDHC_HUMANDrugBank-shows
Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrialIDH3A_PIGPROMISCUOUSPMID 12805shows
Isocitrate dehydrogenase [NAD] subunit beta, mitochondrialIDH3B_PIGPROMISCUOUSPMID 12805shows
Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrialIDH3G_PIGPROMISCUOUSPMID 12805shows
L-xylulose reductaseDCXR_HUMANDrugBank-shows
Malate dehydrogenaseMDH_METJADrugBank-shows
Malate dehydrogenase [NADP], chloroplasticMDHP_FLABIDrugBank-shows
NAD(P) transhydrogenase subunit betaPNTB_RHORUDrugBank-shows
NAD(P) transhydrogenase, mitochondrialNNTM_BOVINDrugBank-shows
NAD(P) transhydrogenase, mitochondrialNNTM_HUMANDrugBank-shows
NAD(P)H-dependent D-xylose reductaseXYL1_CANTEDrugBank-shows
NADH-dependent butanol dehydrogenase, putativeQ9WZS7_THEMADrugBank-shows
NADP-dependent alcohol dehydrogenaseADH8_RANPEDrugBank-shows
NADP-dependent alcohol dehydrogenaseADH_THEBRDrugBank-shows
NADP-dependent alcohol dehydrogenase 6ADH6_YEASTDrugBank-shows
NADP-dependent fatty aldehyde dehydrogenaseALDH_VIBHADrugBank-shows
NADP-dependent glyceraldehyde-3-phosphate dehydrogenaseGAPN_STRMUDrugBank-shows
NADP-dependent malic enzymeMAOX_COLLIDrugBank-shows
NADP-dependent mannitol dehydrogenaseMTDH_AGABIDrugBank-shows
NADPH--cytochrome P450 reductaseNCPR_RATDrugBank-shows
NADPH:adrenodoxin oxidoreductase, mitochondrialADRO_BOVINDrugBank-shows
Nitric oxide synthase, brainNOS1_MOUSEDrugBank-shows
Nitric oxide synthase, brainNOS1_RATDrugBank-shows
Nitrogen metabolite repression regulator NmrAO59919_EMENIDrugBank-shows
Oxidoreductase ydhFYDHF_ECOLIDrugBank-shows
Oxidoreductase, aldo/keto reductase familyQ9X0A2_THEMADrugBank-shows
Oxidoreductase, short chain dehydrogenase/reductase familyQ9WYS2_THEMADrugBank-shows
Probable inorganic polyphosphate/ATP-NAD kinasePPNK_ARCFUDrugBank-shows
Prostaglandin f synthaseQ9GV41_9TRYPDrugBank-shows
Prostaglandin reductase 1PTGR1_CAVPODrugBank-shows
Prostaglandin-E(2) 9-reductasePE2R_RABITDrugBank-shows
Protein iolSIOLS_BACSUDrugBank-shows
Pteridine reductase 1PTR1_LEIMADrugBank-shows
Putative ketoacyl reductaseACT3_STRCODrugBank-shows
Putative pteridine reductase 2Q8I814_TRYCRDrugBank-shows
Putative uncharacterized proteinO29370_ARCFUDrugBank-shows
Putative uncharacterized proteinO29428_ARCFUDrugBank-shows
Quinone oxidoreductaseQOR_HUMANDrugBank-shows
Sepiapterin reductaseSPRE_HUMANDrugBank-shows
Sepiapterin reductaseSPRE_MOUSEDrugBank-shows
Shikimate dehydrogenaseAROE_ECOLIDrugBank-shows
Shikimate dehydrogenaseAROE_METJADrugBank-shows
SnifferQ9W3H4_DROMEDrugBank-shows
Sulfite reductase [NADPH] flavoprotein alpha-componentCYSJ_ECOLIDrugBank-shows
Tropinone reductase 1TRN1_DATSTDrugBank-shows
Tropinone reductase 2TRN2_DATSTDrugBank-shows
Uncharacterized protein At5g02240Y5224_ARATHDrugBank-shows
Synonyms:
2'-O-phosphonoadenosine 5'-{3-[1-(3-carbamoylpyridinio)-1,4-anhydro-D-ribitol-5-yl] dihydrogen diphosphate}
53-59-8
beta-Nicotinamide adenine dinucleotide phosphate
C00006
CHEBI:18009
coenzyme II
DivK1c_000706
IDI1_000706
KBio1_000706
KBio2_002010
KBio2_004578
KBio2_007146
KBioGR_001523
KBioSS_002010
LS-187683
NADP
NADP(+)
NADP+
NAP
NDP
Nicotinamide adenine dinucleotide phosphate
NINDS_000706
oxidized nicotinamide-adenine dinucleotide phosphate
SPBio_000085
Spectrum2_000023
Spectrum4_000862
Spectrum5_001481
Spectrum_001530
TPN
Triphosphopyridine nucleotide
[(2r,3r,4r,5r)-5-(6-aminopurin-9-yl)-3-hydroxy-4-phosphonooxy-tetrahydrofu